Desaulniers JP - Search Results

1

Inhibition of ErbB2(Her2) expression with small molecule transcription factor mimics.

Lee LW, Taylor CE, Desaulniers JP, Zhang M, Højfeldt JW, Pan Q, Mapp AK. Lee LW, et al. Among authors: desaulniers jp. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6233-6. doi: 10.1016/j.bmcl.2009.08.090. Epub 2009 Sep 1. Bioorg Med Chem Lett. 2009. PMID: 19782563 Free PMC article.

2

Expanding the repertoire of small molecule transcriptional activation domains.

Casey RJ, Desaulniers JP, Hojfeldt JW, Mapp AK. Casey RJ, et al. Among authors: desaulniers jp. Bioorg Med Chem. 2009 Feb 1;17(3):1034-43. doi: 10.1016/j.bmc.2008.02.045. Epub 2008 Feb 16. Bioorg Med Chem. 2009. PMID: 18334300

3

Solution conformations of two naturally occurring RNA nucleosides: 3-methyluridine and 3-methylpseudouridine.

Desaulniers JP, Chui HM, Chow CS. Desaulniers JP, et al. Bioorg Med Chem. 2005 Dec 15;13(24):6777-81. doi: 10.1016/j.bmc.2005.07.061. Epub 2005 Aug 24. Bioorg Med Chem. 2005. PMID: 16125393

4

NMR conformational analysis of p-tolyl furanopyrimidine 2'-deoxyribonucleoside and crystal structure of its 3',5'-di-O-acetyl derivative.

Esho N, Desaulniers JP, Davies B, Chui HM, Rao MS, Chow CS, Szafert S, Dembinski R. Esho N, et al. Among authors: desaulniers jp. Bioorg Med Chem. 2005 Feb 15;13(4):1231-8. doi: 10.1016/j.bmc.2004.11.013. Bioorg Med Chem. 2005. PMID: 15670932

5

Efficient synthesis and cell-based silencing activity of siRNAS that contain triazole backbone linkages.

Efthymiou TC, Huynh V, Oentoro J, Peel B, Desaulniers JP. Efthymiou TC, et al. Among authors: desaulniers jp. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1722-6. doi: 10.1016/j.bmcl.2011.12.104. Epub 2011 Dec 30. Bioorg Med Chem Lett. 2012. PMID: 22260772

6

Efficient synthesis of the GABA_A receptor agonist trans-4-aminocrotonic acid (TACA).

Forrester SG, Foster J, Robert S, Salim L, Desaulniers JP. Forrester SG, et al. Among authors: desaulniers jp. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4512-4513. doi: 10.1016/j.bmcl.2017.07.050. Epub 2017 Jul 20. Bioorg Med Chem Lett. 2017. PMID: 28838689

7

Synthesis of 15N-enriched pseudouridine derivatives.

Desaulniers JP, Ksebati B, Chow CS. Desaulniers JP, et al. Org Lett. 2003 Oct 30;5(22):4093-6. doi: 10.1021/ol035496e. Org Lett. 2003. PMID: 14572257

8

Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m(3)Psi and Psi.

Chui HM, Desaulniers JP, Scaringe SA, Chow CS. Chui HM, et al. Among authors: desaulniers jp. J Org Chem. 2002 Dec 13;67(25):8847-54. doi: 10.1021/jo026364m. J Org Chem. 2002. PMID: 12467398

9

Gene-silencing properties of siRNAs that contain internal amide-bond linkages.

Gong W, Desaulniers JP. Gong W, et al. Among authors: desaulniers jp. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6934-7. doi: 10.1016/j.bmcl.2012.09.009. Epub 2012 Sep 20. Bioorg Med Chem Lett. 2012. PMID: 23062704

10

Evaluation of siRNAs that contain internal variable-length spacer linkages.

Efthymiou TC, Peel B, Huynh V, Desaulniers JP. Efthymiou TC, et al. Among authors: desaulniers jp. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5590-4. doi: 10.1016/j.bmcl.2012.07.006. Epub 2012 Jul 16. Bioorg Med Chem Lett. 2012. PMID: 22850216

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