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EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells.
De Weer A, Van der Meulen J, Rondou P, Taghon T, Konrad TA, De Preter K, Mestdagh P, Van Maerken T, Van Roy N, Jeison M, Yaniv I, Cauwelier B, Noens L, Poirel HA, Vandenberghe P, Lambert F, De Paepe A, Sánchez MG, Odero M, Verhasselt B, Philippé J, Vandesompele J, Wieser R, Dastugue N, Van Vlierberghe P, Poppe B, Speleman F. De Weer A, et al. Among authors: vandesompele j. Br J Haematol. 2011 Aug;154(3):337-48. doi: 10.1111/j.1365-2141.2011.08737.x. Epub 2011 May 14. Br J Haematol. 2011. PMID: 21569010 Free article.
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours.
Mestdagh P, Fredlund E, Pattyn F, Rihani A, Van Maerken T, Vermeulen J, Kumps C, Menten B, De Preter K, Schramm A, Schulte J, Noguera R, Schleiermacher G, Janoueix-Lerosey I, Laureys G, Powel R, Nittner D, Marine JC, Ringnér M, Speleman F, Vandesompele J. Mestdagh P, et al. Among authors: vandesompele j. Oncogene. 2010 Jun 17;29(24):3583-92. doi: 10.1038/onc.2010.106. Epub 2010 Apr 12. Oncogene. 2010. PMID: 20383195
MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival.
Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, Fischer M, Zapatka M, Brors B, Savelyeva L, Sagulenko V, Speleman F, Schwab M, Westermann F. Afanasyeva EA, et al. Among authors: vandesompele j. Cell Death Differ. 2011 Jun;18(6):974-84. doi: 10.1038/cdd.2010.164. Epub 2011 Jan 14. Cell Death Differ. 2011. PMID: 21233845 Free PMC article.
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
Vandesompele J, Van Roy N, Van Gele M, Laureys G, Ambros P, Heimann P, Devalck C, Schuuring E, Brock P, Otten J, Gyselinck J, De Paepe A, Speleman F. Vandesompele J, et al. Genes Chromosomes Cancer. 1998 Oct;23(2):141-52. doi: 10.1002/(sici)1098-2264(199810)23:2<141::aid-gcc7>3.0.co;2-2. Genes Chromosomes Cancer. 1998. PMID: 9739017
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.
Mestdagh P, Fredlund E, Pattyn F, Schulte JH, Muth D, Vermeulen J, Kumps C, Schlierf S, De Preter K, Van Roy N, Noguera R, Laureys G, Schramm A, Eggert A, Westermann F, Speleman F, Vandesompele J. Mestdagh P, et al. Among authors: vandesompele j. Oncogene. 2010 Mar 4;29(9):1394-404. doi: 10.1038/onc.2009.429. Epub 2009 Nov 30. Oncogene. 2010. PMID: 19946337
338 results