O'Shea JJ - Search Results

1

The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.

Kimura A, Rieger MA, Simone JM, Chen W, Wickre MC, Zhu BM, Hoppe PS, O'Shea JJ, Schroeder T, Hennighausen L. Kimura A, et al. Blood. 2009 Nov 19;114(21):4721-8. doi: 10.1182/blood-2009-04-216390. Epub 2009 Sep 24. Blood. 2009. PMID: 19779039 Free PMC article.

2

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

Oakes SA, Candotti F, Johnston JA, Chen YQ, Ryan JJ, Taylor N, Liu X, Hennighausen L, Notarangelo LD, Paul WE, Blaese RM, O'Shea JJ. Oakes SA, et al. Immunity. 1996 Dec;5(6):605-15. doi: 10.1016/s1074-7613(00)80274-5. Immunity. 1996. PMID: 8986719 Free article.

3

The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators.

Centola M, Wood G, Frucht DM, Galon J, Aringer M, Farrell C, Kingma DW, Horwitz ME, Mansfield E, Holland SM, O'Shea JJ, Rosenberg HF, Malech HL, Kastner DL. Centola M, et al. Blood. 2000 May 15;95(10):3223-31. Blood. 2000. PMID: 10807793 Free article.

4

Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity.

Visconti R, Gadina M, Chiariello M, Chen EH, Stancato LF, Gutkind JS, O'Shea JJ. Visconti R, et al. Blood. 2000 Sep 1;96(5):1844-52. Blood. 2000. PMID: 10961885 Free article.

5

Jak3 negatively regulates dendritic-cell cytokine production and survival.

Yamaoka K, Min B, Zhou YJ, Paul WE, O'shea JJ. Yamaoka K, et al. Blood. 2005 Nov 1;106(9):3227-33. doi: 10.1182/blood-2005-02-0769. Epub 2005 Jul 14. Blood. 2005. PMID: 16020505 Free PMC article.

6

Identification of an acquired mutation in Jak2 provides molecular insights into the pathogenesis of myeloproliferative disorders.

Pesu M, O'Shea J, Hennighausen L, Silvennoinen O. Pesu M, et al. Mol Interv. 2005 Aug;5(4):211-5. doi: 10.1124/mi.5.4.4. Mol Interv. 2005. PMID: 16123535 No abstract available.

7

Stat5a/b are essential for normal lymphoid development and differentiation.

Yao Z, Cui Y, Watford WT, Bream JH, Yamaoka K, Hissong BD, Li D, Durum SK, Jiang Q, Bhandoola A, Hennighausen L, O'Shea JJ. Yao Z, et al. Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1000-5. doi: 10.1073/pnas.0507350103. Epub 2006 Jan 17. Proc Natl Acad Sci U S A. 2006. PMID: 16418296 Free PMC article.

8

Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma.

Pesu M, Muul L, Kanno Y, O'Shea JJ. Pesu M, et al. Blood. 2006 Aug 1;108(3):983-5. doi: 10.1182/blood-2005-09-3824. Epub 2006 Apr 20. Blood. 2006. PMID: 16627761 Free PMC article.

9

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.

Chen Z, Laurence A, Kanno Y, Pacher-Zavisin M, Zhu BM, Tato C, Yoshimura A, Hennighausen L, O'Shea JJ. Chen Z, et al. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8137-42. doi: 10.1073/pnas.0600666103. Epub 2006 May 12. Proc Natl Acad Sci U S A. 2006. PMID: 16698929 Free PMC article.

10

Nonredundant roles for Stat5a/b in directly regulating Foxp3.

Yao Z, Kanno Y, Kerenyi M, Stephens G, Durant L, Watford WT, Laurence A, Robinson GW, Shevach EM, Moriggl R, Hennighausen L, Wu C, O'Shea JJ. Yao Z, et al. Blood. 2007 May 15;109(10):4368-75. doi: 10.1182/blood-2006-11-055756. Epub 2007 Jan 16. Blood. 2007. PMID: 17227828 Free PMC article.

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