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Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.
Tammam J, Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, Hardwick J, Scott M, Winter C, Bristow L, Elbi C, Reilly JF, Look T, Draetta G, Van der Ploeg L, Kohl NE, Strack PR, Majumder PK. Tammam J, et al. Among authors: dai x. Br J Pharmacol. 2009 Nov;158(5):1183-95. doi: 10.1111/j.1476-5381.2009.00389.x. Epub 2009 Sep 23. Br J Pharmacol. 2009. PMID: 19775282 Free PMC article.
Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
Rao SS, O'Neil J, Liberator CD, Hardwick JS, Dai X, Zhang T, Tyminski E, Yuan J, Kohl NE, Richon VM, Van der Ploeg LH, Carroll PM, Draetta GF, Look AT, Strack PR, Winter CG. Rao SS, et al. Among authors: dai x. Cancer Res. 2009 Apr 1;69(7):3060-8. doi: 10.1158/0008-5472.CAN-08-4295. Epub 2009 Mar 24. Cancer Res. 2009. PMID: 19318552
Cisplatin exposure dysregulates insulin secretion in male and female mice.
Basu L, Grieco-St-Pierre L, Ching MEA, Stead JDH, Hanson AA, Palaniyandi J, van Zyl EP, Hoyeck MP, McKay KS, van Allen KA, Lee H, Dai XQ, Bautista A, Fadzeyeva E, Mulvihill EE, Yauk CL, Mennigen JA, MacDonald PE, Bruin JE. Basu L, et al. Among authors: dai xq. Diabetes. 2025 Jan 14:db240419. doi: 10.2337/db24-0419. Online ahead of print. Diabetes. 2025. PMID: 39808439
8,487 results