Bumpus SB - Search Results

1

A proteomics approach to discovering natural products and their biosynthetic pathways.

Bumpus SB, Evans BS, Thomas PM, Ntai I, Kelleher NL. Bumpus SB, et al. Nat Biotechnol. 2009 Oct;27(10):951-6. doi: 10.1038/nbt.1565. Epub 2009 Sep 20. Nat Biotechnol. 2009. PMID: 19767731 Free PMC article.

2

Accessing natural product biosynthetic processes by mass spectrometry.

Bumpus SB, Kelleher NL. Bumpus SB, et al. Curr Opin Chem Biol. 2008 Oct;12(5):475-82. doi: 10.1016/j.cbpa.2008.07.022. Curr Opin Chem Biol. 2008. PMID: 18706516 Free PMC article. Review.

3

Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry.

Dorrestein PC, Bumpus SB, Calderone CT, Garneau-Tsodikova S, Aron ZD, Straight PD, Kolter R, Walsh CT, Kelleher NL. Dorrestein PC, et al. Among authors: bumpus sb. Biochemistry. 2006 Oct 24;45(42):12756-66. doi: 10.1021/bi061169d. Biochemistry. 2006. PMID: 17042494 Free PMC article.

4

Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display.

Yin J, Straight PD, Hrvatin S, Dorrestein PC, Bumpus SB, Jao C, Kelleher NL, Kolter R, Walsh CT. Yin J, et al. Among authors: bumpus sb. Chem Biol. 2007 Mar;14(3):303-12. doi: 10.1016/j.chembiol.2007.01.006. Chem Biol. 2007. PMID: 17379145

5

Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis.

Bumpus SB, Magarvey NA, Kelleher NL, Walsh CT, Calderone CT. Bumpus SB, et al. J Am Chem Soc. 2008 Sep 3;130(35):11614-6. doi: 10.1021/ja8040042. Epub 2008 Aug 12. J Am Chem Soc. 2008. PMID: 18693732 Free PMC article.

6

Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity.

Vagstad AL, Bumpus SB, Belecki K, Kelleher NL, Townsend CA. Vagstad AL, et al. Among authors: bumpus sb. J Am Chem Soc. 2012 Apr 18;134(15):6865-77. doi: 10.1021/ja3016389. Epub 2012 Apr 9. J Am Chem Soc. 2012. PMID: 22452347 Free PMC article.

7

A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both alpha- and beta-ketone reduction during chain growth.

Calderone CT, Bumpus SB, Kelleher NL, Walsh CT, Magarvey NA. Calderone CT, et al. Among authors: bumpus sb. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12809-14. doi: 10.1073/pnas.0806305105. Epub 2008 Aug 22. Proc Natl Acad Sci U S A. 2008. PMID: 18723688 Free PMC article.

8

The loading module of mycosubtilin: an adenylation domain with fatty acid selectivity.

Hansen DB, Bumpus SB, Aron ZD, Kelleher NL, Walsh CT. Hansen DB, et al. Among authors: bumpus sb. J Am Chem Soc. 2007 May 23;129(20):6366-7. doi: 10.1021/ja070890j. Epub 2007 May 2. J Am Chem Soc. 2007. PMID: 17472382 No abstract available.

9

The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis.

Hollenhorst MA, Bumpus SB, Matthews ML, Bollinger JM Jr, Kelleher NL, Walsh CT. Hollenhorst MA, et al. Among authors: bumpus sb. J Am Chem Soc. 2010 Nov 10;132(44):15773-81. doi: 10.1021/ja1072367. J Am Chem Soc. 2010. PMID: 20945916 Free PMC article.

10

Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics.

Molohon KJ, Melby JO, Lee J, Evans BS, Dunbar KL, Bumpus SB, Kelleher NL, Mitchell DA. Molohon KJ, et al. Among authors: bumpus sb. ACS Chem Biol. 2011 Dec 16;6(12):1307-13. doi: 10.1021/cb200339d. Epub 2011 Oct 6. ACS Chem Biol. 2011. PMID: 21950656 Free PMC article.

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