Leone M - Search Results

1

The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam.

Leone M, Cellitti J, Pellecchia M. Leone M, et al. BMC Struct Biol. 2009 Sep 18;9:59. doi: 10.1186/1472-6807-9-59. BMC Struct Biol. 2009. PMID: 19765305 Free PMC article.

2

Selective incorporation of 19F-labeled Trp side chains for NMR-spectroscopy-based ligand-protein interaction studies.

Leone M, Rodriguez-Mias RA, Pellecchia M. Leone M, et al. Chembiochem. 2003 Jul 7;4(7):649-50. doi: 10.1002/cbic.200300597. Chembiochem. 2003. PMID: 12851935 No abstract available.

3

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins.

Kitada S, Leone M, Sareth S, Zhai D, Reed JC, Pellecchia M. Kitada S, et al. Among authors: leone m. J Med Chem. 2003 Sep 25;46(20):4259-64. doi: 10.1021/jm030190z. J Med Chem. 2003. PMID: 13678404

4

Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins.

Leone M, Zhai D, Sareth S, Kitada S, Reed JC, Pellecchia M. Leone M, et al. Cancer Res. 2003 Dec 1;63(23):8118-21. Cancer Res. 2003. PMID: 14678963

5

Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

Becattini B, Kitada S, Leone M, Monosov E, Chandler S, Zhai D, Kipps TJ, Reed JC, Pellecchia M. Becattini B, et al. Among authors: leone m. Chem Biol. 2004 Mar;11(3):389-95. doi: 10.1016/j.chembiol.2004.02.020. Chem Biol. 2004. PMID: 15123268

6

Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.

Becattini B, Sareth S, Zhai D, Crowell KJ, Leone M, Reed JC, Pellecchia M. Becattini B, et al. Among authors: leone m. Chem Biol. 2004 Aug;11(8):1107-17. doi: 10.1016/j.chembiol.2004.05.022. Chem Biol. 2004. PMID: 15324812

7

Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex.

Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S. Santelli E, et al. Among authors: leone m. J Biol Chem. 2005 Oct 7;280(40):34278-87. doi: 10.1074/jbc.M506707200. Epub 2005 Aug 4. J Biol Chem. 2005. PMID: 16085652 Free article.

8

A structure-based approach to retinoid X receptor-alpha inhibition.

Stebbins JL, Jung D, Leone M, Zhang XK, Pellecchia M. Stebbins JL, et al. Among authors: leone m. J Biol Chem. 2006 Jun 16;281(24):16643-8. doi: 10.1074/jbc.M600318200. Epub 2006 Apr 10. J Biol Chem. 2006. PMID: 16606625 Free article.

9

NMR assignment of the phosphotyrosine binding (PTB) domain of tensin.

Leone M, Yu EC, Liddington R, Pellecchia M. Leone M, et al. J Biomol NMR. 2006;36 Suppl 1:40. doi: 10.1007/s10858-006-9011-3. Epub 2006 May 17. J Biomol NMR. 2006. PMID: 16705357 No abstract available.

10

Structure-activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid.

Becattini B, Culmsee C, Leone M, Zhai D, Zhang X, Crowell KJ, Rega MF, Landshamer S, Reed JC, Plesnila N, Pellecchia M. Becattini B, et al. Among authors: leone m. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12602-6. doi: 10.1073/pnas.0603460103. Epub 2006 Aug 4. Proc Natl Acad Sci U S A. 2006. PMID: 16891420 Free PMC article.

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