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Pravastatin reduces myocardial infarct size via increasing protein kinase C-dependent nitric oxide, decreasing oxyradicals and opening the mitochondrial adenosine triphosphate-sensitive potassium channels in rabbits.
Bao N, Minatoguchi S, Kobayashi H, Yasuda S, Kawamura I, Iwasa M, Yamaki T, Sumi S, Misao Y, Arai M, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H. Bao N, et al. Among authors: kobayashi h. Circ J. 2007 Oct;71(10):1622-8. doi: 10.1253/circj.71.1622. Circ J. 2007. PMID: 17895562 Free article.
Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.
Yasuda S, Kobayashi H, Iwasa M, Kawamura I, Sumi S, Narentuoya B, Yamaki T, Ushikoshi H, Nishigaki K, Nagashima K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Yasuda S, et al. Among authors: kobayashi h. Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1558-65. doi: 10.1152/ajpheart.00712.2008. Epub 2009 Mar 13. Am J Physiol Heart Circ Physiol. 2009. PMID: 19286954 Free article.
Acarbose reduces myocardial infarct size by preventing postprandial hyperglycemia and hydroxyl radical production and opening mitochondrial KATP channels in rabbits.
Minatoguchi S, Zhang Z, Bao N, Kobayashi H, Yasuda S, Iwasa M, Sumi S, Kawamura I, Yamada Y, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H. Minatoguchi S, et al. Among authors: kobayashi h. J Cardiovasc Pharmacol. 2009 Jul;54(1):25-30. doi: 10.1097/FJC.0b013e3181a98b53. J Cardiovasc Pharmacol. 2009. PMID: 19487955
Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits.
Iwasa M, Kobayashi H, Yasuda S, Kawamura I, Sumi S, Yamada Y, Shiraki T, Yamaki T, Ushikoshi H, Aoyama T, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Iwasa M, et al. Among authors: kobayashi h. J Cardiovasc Pharmacol. 2010 Jun;55(6):625-34. doi: 10.1097/FJC.0b013e3181dcd240. J Cardiovasc Pharmacol. 2010. PMID: 20351564
Postconditioning effect of granulocyte colony-stimulating factor is mediated through activation of risk pathway and opening of the mitochondrial KATP channels.
Sumi S, Kobayashi H, Yasuda S, Iwasa M, Yamaki T, Yamada Y, Ushikoshi H, Hattori A, Aoyama T, Nishigaki K, Takemura G, Minatoguchi S. Sumi S, et al. Among authors: kobayashi h. Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1174-82. doi: 10.1152/ajpheart.00116.2010. Epub 2010 Aug 6. Am J Physiol Heart Circ Physiol. 2010. PMID: 20693399 Free article.
Treatment of leg ischemia with biodegradable gelatin hydrogel microspheres incorporating granulocyte colony-stimulating factor.
Kawamura I, Takemura G, Tsujimoto A, Watanabe T, Kanamori H, Esaki M, Kobayashi H, Takeyama T, Kawaguchi T, Goto K, Maruyama R, Fujiwara T, Fujiwara H, Tabata Y, Minatoguchi S. Kawamura I, et al. Among authors: kobayashi h. J Cardiovasc Pharmacol. 2011 Apr;57(4):416-23. doi: 10.1097/FJC.0b013e31820c9776. J Cardiovasc Pharmacol. 2011. PMID: 21242812
9,535 results