Crighton D - Search Results

1

TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival.

Huser CA, Pringle MA, Heath VJ, Bell AK, Kendrick H, Smalley MJ, Crighton D, Ryan KM, Gusterson BA, Stein T. Huser CA, et al. Among authors: crighton d. Cell Death Differ. 2010 Feb;17(2):304-15. doi: 10.1038/cdd.2009.126. Epub 2009 Sep 11. Cell Death Differ. 2010. PMID: 19745830

2

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death.

Crighton D, O'Prey J, Bell HS, Ryan KM. Crighton D, et al. Cell Death Differ. 2007 Jun;14(6):1071-9. doi: 10.1038/sj.cdd.4402108. Epub 2007 Feb 16. Cell Death Differ. 2007. PMID: 17304243

3

Splicing DNA-damage responses to tumour cell death.

Crighton D, Ryan KM. Crighton D, et al. Biochim Biophys Acta. 2004 Dec 10;1705(1):3-15. doi: 10.1016/j.bbcan.2004.09.001. Biochim Biophys Acta. 2004. PMID: 15585169 Review.

4

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.

Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. Crighton D, et al. Cell. 2006 Jul 14;126(1):121-34. doi: 10.1016/j.cell.2006.05.034. Cell. 2006. PMID: 16839881 Free article.

5

DRAM links autophagy to p53 and programmed cell death.

Crighton D, Wilkinson S, Ryan KM. Crighton D, et al. Autophagy. 2007 Jan-Feb;3(1):72-4. doi: 10.4161/auto.3438. Epub 2007 Jan 28. Autophagy. 2007. PMID: 17102582 Review.

6

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

Long JS, Crighton D, O'Prey J, Mackay G, Zheng L, Palmer TM, Gottlieb E, Ryan KM. Long JS, et al. Among authors: crighton d. Mol Cell. 2013 May 9;50(3):394-406. doi: 10.1016/j.molcel.2013.03.016. Epub 2013 Apr 18. Mol Cell. 2013. PMID: 23603120 Free article.

7

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival.

Croft DR, Crighton D, Samuel MS, Lourenco FC, Munro J, Wood J, Bensaad K, Vousden KH, Sansom OJ, Ryan KM, Olson MF. Croft DR, et al. Among authors: crighton d. Cell Res. 2011 Apr;21(4):666-82. doi: 10.1038/cr.2010.154. Epub 2010 Nov 16. Cell Res. 2011. PMID: 21079653 Free PMC article.

8

p53-mediated induction of Noxa and p53AIP1 requires NFkappaB.

O'Prey J, Crighton D, Martin AG, Vousden KH, Fearnhead HO, Ryan KM. O'Prey J, et al. Among authors: crighton d. Cell Cycle. 2010 Mar 1;9(5):947-52. doi: 10.4161/cc.9.5.10872. Epub 2010 Mar 7. Cell Cycle. 2010. PMID: 20160496

9

RNA polymerase III transcription can be derepressed by oncogenes or mutations that compromise p53 function in tumours and Li-Fraumeni syndrome.

Stein T, Crighton D, Boyle JM, Varley JM, White RJ. Stein T, et al. Among authors: crighton d. Oncogene. 2002 May 2;21(19):2961-70. doi: 10.1038/sj.onc.1205372. Oncogene. 2002. PMID: 12082526

10

p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death.

Baudot AD, Crighton D, O'Prey J, Somers J, Sierra Gonzalez P, Ryan KM. Baudot AD, et al. Among authors: crighton d. Cell Cycle. 2016 Sep;15(17):2299-308. doi: 10.1080/15384101.2016.1191714. Epub 2016 Jun 17. Cell Cycle. 2016. PMID: 27315169 Free PMC article.

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