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PH domain leucine-rich repeat protein phosphatase 1 contributes to maintain the activation of the PI3K/Akt pro-survival pathway in Huntington's disease striatum.
Saavedra A, García-Martínez JM, Xifró X, Giralt A, Torres-Peraza JF, Canals JM, Díaz-Hernández M, Lucas JJ, Alberch J, Pérez-Navarro E. Saavedra A, et al. Among authors: torres peraza jf. Cell Death Differ. 2010 Feb;17(2):324-35. doi: 10.1038/cdd.2009.127. Epub 2009 Sep 11. Cell Death Differ. 2010. PMID: 19745829
Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels.
Carretón O, Giralt A, Torres-Peraza JF, Brito V, Lucas JJ, Ginés S, Canals JM, Alberch J. Carretón O, et al. Among authors: torres peraza jf. Exp Neurol. 2012 Oct;237(2):335-45. doi: 10.1016/j.expneurol.2012.06.033. Epub 2012 Jul 6. Exp Neurol. 2012. PMID: 22776425
Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.
Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Graham RK, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, Alberch J, Wesseling JF, Pérez-Otaño I. Marco S, et al. Nat Med. 2013 Aug;19(8):1030-8. doi: 10.1038/nm.3246. Epub 2013 Jul 14. Nat Med. 2013. PMID: 23852340 Free PMC article.
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