Ng CH - Search Results

1

Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.

Ng CH, Mok SZ, Koh C, Ouyang X, Fivaz ML, Tan EK, Dawson VL, Dawson TM, Yu F, Lim KL. Ng CH, et al. J Neurosci. 2009 Sep 9;29(36):11257-62. doi: 10.1523/JNEUROSCI.2375-09.2009. J Neurosci. 2009. PMID: 19741132 Free PMC article.

2

Interconversion of the kinetic identities of the tandem catalytic domains of receptor-like protein-tyrosine phosphatase PTPalpha by two point mutations is synergistic and substrate-dependent.

Lim KL, Kolatkar PR, Ng KP, Ng CH, Pallen CJ. Lim KL, et al. Among authors: ng kp, ng ch. J Biol Chem. 1998 Oct 30;273(44):28986-93. doi: 10.1074/jbc.273.44.28986. J Biol Chem. 1998. PMID: 9786903 Free article.

3

Catalytic activation of the membrane distal domain of protein tyrosine phosphatase epsilon, but not CD45, by two point mutations.

Lim KL, Ng CH, Pallen CJ. Lim KL, et al. Among authors: ng ch. Biochim Biophys Acta. 1999 Oct 12;1434(2):275-83. doi: 10.1016/s0167-4838(99)00189-2. Biochim Biophys Acta. 1999. PMID: 10525146

4

Calmodulin binds to and inhibits the activity of the membrane distal catalytic domain of receptor protein-tyrosine phosphatase alpha.

Liang L, Lim KL, Seow KT, Ng CH, Pallen CJ. Liang L, et al. Among authors: ng ch. J Biol Chem. 2000 Sep 29;275(39):30075-81. doi: 10.1074/jbc.M004843200. J Biol Chem. 2000. PMID: 10893241 Free article.

5

Genetic models of Parkinson disease.

Lim KL, Ng CH. Lim KL, et al. Among authors: ng ch. Biochim Biophys Acta. 2009 Jul;1792(7):604-15. doi: 10.1016/j.bbadis.2008.10.005. Epub 2008 Oct 22. Biochim Biophys Acta. 2009. PMID: 19000757 Free article. Review.

6

AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease.

Ng CH, Guan MS, Koh C, Ouyang X, Yu F, Tan EK, O'Neill SP, Zhang X, Chung J, Lim KL. Ng CH, et al. J Neurosci. 2012 Oct 10;32(41):14311-7. doi: 10.1523/JNEUROSCI.0499-12.2012. J Neurosci. 2012. PMID: 23055502 Free PMC article.

7

Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila.

Angeles DC, Ho P, Chua LL, Wang C, Yap YW, Ng C, Zhou Zd, Lim KL, Wszolek ZK, Wang HY, Tan EK. Angeles DC, et al. Hum Mol Genet. 2014 Jun 15;23(12):3157-65. doi: 10.1093/hmg/ddu026. Epub 2014 Jan 23. Hum Mol Genet. 2014. PMID: 24459295 Free PMC article.

8

Pharmacological or Genetic Activation of Hsp70 Protects against Loss of Parkin Function.

Zhang CW, Adeline HB, Chai BH, Hong ET, Ng CH, Lim KL. Zhang CW, et al. Among authors: ng ch. Neurodegener Dis. 2016;16(5-6):304-16. doi: 10.1159/000443668. Epub 2016 Feb 18. Neurodegener Dis. 2016. PMID: 26886023

9

Drosophila expressing human SOD1 successfully recapitulates mitochondrial phenotypic features of familial amyotrophic lateral sclerosis.

Gallart-Palau X, Ng CH, Ribera J, Sze SK, Lim KL. Gallart-Palau X, et al. Among authors: ng ch. Neurosci Lett. 2016 Jun 15;624:47-52. doi: 10.1016/j.neulet.2016.05.006. Epub 2016 May 7. Neurosci Lett. 2016. PMID: 27163198

10

Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.

Nucifora FC Jr, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, Dawson TM, Smith W, Lim KL, Ross CA. Nucifora FC Jr, et al. Among authors: ng ch. Nat Commun. 2016 Jun 7;7:11792. doi: 10.1038/ncomms11792. Nat Commun. 2016. PMID: 27273569 Free PMC article.

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