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Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly.
Toba S, Tamura Y, Kumamoto K, Yamada M, Takao K, Hattori S, Miyakawa T, Kataoka Y, Azuma M, Hayasaka K, Amamoto M, Tominaga K, Wynshaw-Boris A, Wanibuchi H, Oka Y, Sato M, Kato M, Hirotsune S. Toba S, et al. Among authors: sato m. Sci Rep. 2013;3:1224. doi: 10.1038/srep01224. Epub 2013 Feb 6. Sci Rep. 2013. PMID: 23390575 Free PMC article.
DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation.
Okamoto M, Iguchi T, Hattori T, Matsuzaki S, Koyama Y, Taniguchi M, Komada M, Xie MJ, Yagi H, Shimizu S, Konishi Y, Omi M, Yoshimi T, Tachibana T, Fujieda S, Katayama T, Ito A, Hirotsune S, Tohyama M, Sato M. Okamoto M, et al. Among authors: sato m. J Neurosci. 2015 Feb 18;35(7):2942-58. doi: 10.1523/JNEUROSCI.5029-13.2015. J Neurosci. 2015. PMID: 25698733 Free PMC article.
Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.
Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T. Matsumura K, et al. Among authors: sato m. Nat Commun. 2020 Feb 26;11(1):859. doi: 10.1038/s41467-020-14697-z. Nat Commun. 2020. PMID: 32103003 Free PMC article.
Autism-associated protein kinase D2 regulates embryonic cortical neuron development.
Matsumura K, Baba M, Nagayasu K, Yamamoto K, Kondo M, Kitagawa K, Takemoto T, Seiriki K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Kuriu T, Iguchi T, Sato M, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T. Matsumura K, et al. Among authors: sato m. Biochem Biophys Res Commun. 2019 Nov 12;519(3):626-632. doi: 10.1016/j.bbrc.2019.09.048. Epub 2019 Sep 18. Biochem Biophys Res Commun. 2019. PMID: 31540692
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