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4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.
Pizzimenti S, Menegatti E, Berardi D, Toaldo C, Pettazzoni P, Minelli R, Giglioni B, Cerbone A, Dianzani MU, Ferretti C, Barrera G. Pizzimenti S, et al. Among authors: toaldo c. J Nutr Biochem. 2010 Sep;21(9):818-26. doi: 10.1016/j.jnutbio.2009.06.005. Epub 2009 Sep 3. J Nutr Biochem. 2010. PMID: 19733043
4-hydroxynonenal and cell cycle.
Barrera G, Pizzimenti S, Laurora S, Briatore F, Toaldo C, Dianzani MU. Barrera G, et al. Among authors: toaldo c. Biofactors. 2005;24(1-4):151-7. doi: 10.1002/biof.5520240118. Biofactors. 2005. PMID: 16403975 Free article.
Induction of cell cycle arrest and DNA damage by the HDAC inhibitor panobinostat (LBH589) and the lipid peroxidation end product 4-hydroxynonenal in prostate cancer cells.
Pettazzoni P, Pizzimenti S, Toaldo C, Sotomayor P, Tagliavacca L, Liu S, Wang D, Minelli R, Ellis L, Atadja P, Ciamporcero E, Dianzani MU, Barrera G, Pili R. Pettazzoni P, et al. Among authors: toaldo c. Free Radic Biol Med. 2011 Jan 15;50(2):313-22. doi: 10.1016/j.freeradbiomed.2010.11.011. Epub 2010 Nov 13. Free Radic Biol Med. 2011. PMID: 21078383
Nuclear factor erythroid 2-related factor-2 activity controls 4-hydroxynonenal metabolism and activity in prostate cancer cells.
Pettazzoni P, Ciamporcero E, Medana C, Pizzimenti S, Dal Bello F, Minero VG, Toaldo C, Minelli R, Uchida K, Dianzani MU, Pili R, Barrera G. Pettazzoni P, et al. Among authors: toaldo c. Free Radic Biol Med. 2011 Oct 15;51(8):1610-8. doi: 10.1016/j.freeradbiomed.2011.07.009. Epub 2011 Jul 19. Free Radic Biol Med. 2011. PMID: 21816220
25 results