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4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.
Pizzimenti S, Menegatti E, Berardi D, Toaldo C, Pettazzoni P, Minelli R, Giglioni B, Cerbone A, Dianzani MU, Ferretti C, Barrera G. Pizzimenti S, et al. Among authors: barrera g. J Nutr Biochem. 2010 Sep;21(9):818-26. doi: 10.1016/j.jnutbio.2009.06.005. Epub 2009 Sep 3. J Nutr Biochem. 2010. PMID: 19733043
Effect of 4-hydroxynonenal on c-myc expression.
Barrera G, Martinotti S, Fazio V, Manzari V, Paradisi L, Parola M, Frati L, Dianzani MU. Barrera G, et al. Toxicol Pathol. 1987;15(2):238-40. doi: 10.1177/019262338701500219. Toxicol Pathol. 1987. PMID: 3475758
323 results