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Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models.
Minami K, Hasegawa M, Ito H, Nakamura A, Tomii T, Matsumoto M, Orita S, Matsushima S, Miyoshi T, Masuno K, Torii M, Koike K, Shimada S, Kanemasa T, Kihara T, Narita M, Suzuki T, Kato A. Minami K, et al. Among authors: shimada s. J Pharmacol Sci. 2009 Sep;111(1):60-72. doi: 10.1254/jphs.09139fp. Epub 2009 Sep 4. J Pharmacol Sci. 2009. PMID: 19729873 Free article.
The antagonistic activity profile of naloxone in μ-opioid receptor agonist-induced psychological dependence.
Nakamura A, Yasufuku K, Shimada S, Aritomi H, Furue Y, Chiba H, Muramoto M, Takase K, Koike K, Matsumoto T, Shimada T, Watari R, Matsuzaki T, Asaki T, Kanemasa T, Fujita M. Nakamura A, et al. Among authors: shimada s, shimada t. Neurosci Lett. 2020 Sep 14;735:135177. doi: 10.1016/j.neulet.2020.135177. Epub 2020 Jun 20. Neurosci Lett. 2020. PMID: 32569809 Free article.
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds.
Tobinaga H, Kameyama T, Asahi K, Horiguchi T, Oohara M, Tada Y, Fuchino K, Jikihara S, Endoh T, Kurihara N, Kanda Y, Ogawa M, Tamura N, Yagi S, Taniguchi E, Takahara Y, Shimada S, Takeyama C, Yamamoto S, Shinohara S, Kai H. Tobinaga H, et al. Among authors: shimada s. Bioorg Med Chem Lett. 2019 Mar 1;29(5):688-693. doi: 10.1016/j.bmcl.2019.01.039. Epub 2019 Feb 1. Bioorg Med Chem Lett. 2019. PMID: 30728111
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 3: Structure-activity relationships of pyrropyrazolone derivatives.
Tobinaga H, Kameyama T, Asahi K, Horiguchi T, Oohara M, Taoda Y, Hata K, Hasegawa T, Tada Y, Kurihara N, Kanda Y, Yagi S, Tomari M, Tanaka Y, Takahashi F, Taniguchi E, Takahara Y, Shimada S, Takeyama C, Yamamoto S, Shinohara S, Kai H. Tobinaga H, et al. Among authors: shimada s. Bioorg Med Chem Lett. 2020 Dec 15;30(24):127636. doi: 10.1016/j.bmcl.2020.127636. Epub 2020 Oct 22. Bioorg Med Chem Lett. 2020. PMID: 33132115
Differential effects of allopregnanolone and diazepam on social behavior through modulation of neural oscillation dynamics in basolateral amygdala and medial prefrontal cortex.
Yawata Y, Tashima R, Aritomi H, Shimada S, Onodera T, Taishi T, Takasu K, Ogawa K. Yawata Y, et al. Among authors: shimada s. Front Cell Neurosci. 2024 Jun 5;18:1404603. doi: 10.3389/fncel.2024.1404603. eCollection 2024. Front Cell Neurosci. 2024. PMID: 38899227 Free PMC article.
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening.
Tobinaga H, Kameyama T, Oohara M, Kobayashi N, Ohdan M, Ishizuka N, Kume M, Tomari M, Tanaka Y, Takahashi F, Kinoshita H, Shimada S, Shinohara S, Kai H. Tobinaga H, et al. Among authors: shimada s. Bioorg Med Chem Lett. 2018 Jul 15;28(13):2338-2342. doi: 10.1016/j.bmcl.2017.04.060. Epub 2017 Apr 19. Bioorg Med Chem Lett. 2018. PMID: 29805055
1,872 results