Agbandje-McKenna M - Search Results

1

Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints.

Vandenberghe LH, Breous E, Nam HJ, Gao G, Xiao R, Sandhu A, Johnston J, Debyser Z, Agbandje-McKenna M, Wilson JM. Vandenberghe LH, et al. Gene Ther. 2009 Dec;16(12):1416-28. doi: 10.1038/gt.2009.101. Gene Ther. 2009. PMID: 19727141 Free PMC article.

2

A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis.

Zhong L, Zhao W, Wu J, Li B, Zolotukhin S, Govindasamy L, Agbandje-McKenna M, Srivastava A. Zhong L, et al. Mol Ther. 2007 Jul;15(7):1323-30. doi: 10.1038/sj.mt.6300170. Epub 2007 Apr 17. Mol Ther. 2007. PMID: 17440440 Free article.

3

Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.

Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE Jr, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ. Li W, et al. Mol Ther. 2008 Jul;16(7):1252-60. doi: 10.1038/mt.2008.100. Epub 2008 May 20. Mol Ther. 2008. PMID: 18500254 Free PMC article.

4

Molecular characterization of the heparin-dependent transduction domain on the capsid of a novel adeno-associated virus isolate, AAV(VR-942).

Schmidt M, Govindasamy L, Afione S, Kaludov N, Agbandje-McKenna M, Chiorini JA. Schmidt M, et al. J Virol. 2008 Sep;82(17):8911-6. doi: 10.1128/JVI.00672-08. Epub 2008 Jun 4. J Virol. 2008. PMID: 18524816 Free PMC article.

5

Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins.

Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M, Wilson JM. Mays LE, et al. J Immunol. 2009 May 15;182(10):6051-60. doi: 10.4049/jimmunol.0803965. J Immunol. 2009. PMID: 19414756 Free PMC article.

6

Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium.

Li W, Zhang L, Johnson JS, Zhijian W, Grieger JC, Ping-Jie X, Drouin LM, Agbandje-McKenna M, Pickles RJ, Samulski RJ. Li W, et al. Mol Ther. 2009 Dec;17(12):2067-77. doi: 10.1038/mt.2009.155. Epub 2009 Jul 14. Mol Ther. 2009. PMID: 19603002 Free PMC article.

7

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle.

Asokan A, Conway JC, Phillips JL, Li C, Hegge J, Sinnott R, Yadav S, DiPrimio N, Nam HJ, Agbandje-McKenna M, McPhee S, Wolff J, Samulski RJ. Asokan A, et al. Nat Biotechnol. 2010 Jan;28(1):79-82. doi: 10.1038/nbt.1599. Epub 2009 Dec 27. Nat Biotechnol. 2010. PMID: 20037580 Free PMC article.

8

Little vector, big gene transduction: fragmented genome reassembly of adeno-associated virus.

Hirsch ML, Agbandje-McKenna M, Samulski RJ. Hirsch ML, et al. Mol Ther. 2010 Jan;18(1):6-8. doi: 10.1038/mt.2009.280. Mol Ther. 2010. PMID: 20048740 Free PMC article. No abstract available.

9

Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3.

Ling C, Lu Y, Kalsi JK, Jayandharan GR, Li B, Ma W, Cheng B, Gee SW, McGoogan KE, Govindasamy L, Zhong L, Agbandje-McKenna M, Srivastava A. Ling C, et al. Hum Gene Ther. 2010 Dec;21(12):1741-7. doi: 10.1089/hum.2010.075. Hum Gene Ther. 2010. PMID: 20545554 Free PMC article.

10

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.

Petrs-Silva H, Dinculescu A, Li Q, Deng WT, Pang JJ, Min SH, Chiodo V, Neeley AW, Govindasamy L, Bennett A, Agbandje-McKenna M, Zhong L, Li B, Jayandharan GR, Srivastava A, Lewin AS, Hauswirth WW. Petrs-Silva H, et al. Mol Ther. 2011 Feb;19(2):293-301. doi: 10.1038/mt.2010.234. Epub 2010 Nov 2. Mol Ther. 2011. PMID: 21045809 Free PMC article.

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