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The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling.
Micalizzi DS, Christensen KL, Jedlicka P, Coletta RD, Barón AE, Harrell JC, Horwitz KB, Billheimer D, Heichman KA, Welm AL, Schiemann WP, Ford HL. Micalizzi DS, et al. Among authors: welm al. J Clin Invest. 2009 Sep;119(9):2678-90. doi: 10.1172/JCI37815. Epub 2009 Aug 24. J Clin Invest. 2009. PMID: 19726885 Free PMC article.
Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
Song K, Cai X, Dong Y, Wu H, Wei Y, Shankavaram UT, Cui K, Lee Y, Zhu B, Bhattacharjee S, Wang B, Zhang K, Wen A, Wong S, Yu L, Xia L, Welm AL, Bielenberg DR, Camphausen KA, Kang Y, Chen H. Song K, et al. Among authors: welm al. J Clin Invest. 2021 Jan 4;131(1):e129374. doi: 10.1172/JCI129374. J Clin Invest. 2021. PMID: 32960814 Free PMC article.
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.
Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM. Gilbert PM, et al. Among authors: welm al. J Clin Invest. 2010 May;120(5):1535-50. doi: 10.1172/JCI39534. Epub 2010 Apr 12. J Clin Invest. 2010. PMID: 20389018 Free PMC article.
Netrin-4 induces lymphangiogenesis in vivo.
Larrieu-Lahargue F, Welm AL, Thomas KR, Li DY. Larrieu-Lahargue F, et al. Among authors: welm al. Blood. 2010 Jul 1;115(26):5418-26. doi: 10.1182/blood-2009-11-252338. Epub 2010 Apr 20. Blood. 2010. PMID: 20407033 Free PMC article.
Patient-derived xenograft (PDX) models in basic and translational breast cancer research.
Dobrolecki LE, Airhart SD, Alferez DG, Aparicio S, Behbod F, Bentires-Alj M, Brisken C, Bult CJ, Cai S, Clarke RB, Dowst H, Ellis MJ, Gonzalez-Suarez E, Iggo RD, Kabos P, Li S, Lindeman GJ, Marangoni E, McCoy A, Meric-Bernstam F, Piwnica-Worms H, Poupon MF, Reis-Filho J, Sartorius CA, Scabia V, Sflomos G, Tu Y, Vaillant F, Visvader JE, Welm A, Wicha MS, Lewis MT. Dobrolecki LE, et al. Cancer Metastasis Rev. 2016 Dec;35(4):547-573. doi: 10.1007/s10555-016-9653-x. Cancer Metastasis Rev. 2016. PMID: 28025748 Free PMC article. Review.
Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.
Tsai HC, Li H, Van Neste L, Cai Y, Robert C, Rassool FV, Shin JJ, Harbom KM, Beaty R, Pappou E, Harris J, Yen RW, Ahuja N, Brock MV, Stearns V, Feller-Kopman D, Yarmus LB, Lin YC, Welm AL, Issa JP, Minn I, Matsui W, Jang YY, Sharkis SJ, Baylin SB, Zahnow CA. Tsai HC, et al. Among authors: welm al. Cancer Cell. 2012 Mar 20;21(3):430-46. doi: 10.1016/j.ccr.2011.12.029. Cancer Cell. 2012. PMID: 22439938 Free PMC article.
The importance of developing therapies targeting the biological spectrum of metastatic disease.
Zijlstra A, Von Lersner A, Yu D, Borrello L, Oudin M, Kang Y, Sahai E, Fingleton B, Stein U, Cox TR, Price JT, Kato Y, Welm AL, Aguirre-Ghiso JA; Board Members of the Metastasis Research Society. Zijlstra A, et al. Among authors: welm al. Clin Exp Metastasis. 2019 Aug;36(4):305-309. doi: 10.1007/s10585-019-09972-3. Epub 2019 May 17. Clin Exp Metastasis. 2019. PMID: 31102066 Free PMC article.
115 results