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Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways.
Iwanaga R, Wang CA, Micalizzi DS, Harrell JC, Jedlicka P, Sartorius CA, Kabos P, Farabaugh SM, Bradford AP, Ford HL. Iwanaga R, et al. Breast Cancer Res. 2012 Jul 5;14(4):R100. doi: 10.1186/bcr3219. Breast Cancer Res. 2012. PMID: 22765220 Free PMC article.
Loss of prdm1a accelerates melanoma onset and progression.
Iwanaga R, Truong BT, Hsu JY, Lambert KA, Vyas R, Orlicky D, Shellman YG, Tan AC, Ceol C, Artinger KB. Iwanaga R, et al. Mol Carcinog. 2020 Sep;59(9):1052-1063. doi: 10.1002/mc.23236. Epub 2020 Jun 20. Mol Carcinog. 2020. PMID: 32562448 Free PMC article.
Ectopic expression of the CDK inhibitor p21Cip1 enhances deregulated E2F activity and increases cancer cell-specific cytotoxic gene expression mediated by the ARF tumor suppressor promoter.
Kurayoshi K, Shiromoto A, Ozono E, Iwanaga R, Bradford AP, Araki K, Ohtani K. Kurayoshi K, et al. Among authors: iwanaga r. Biochem Biophys Res Commun. 2017 Jan 29;483(1):107-114. doi: 10.1016/j.bbrc.2016.12.185. Epub 2016 Dec 29. Biochem Biophys Res Commun. 2017. PMID: 28042030
DEAD/H Box 5 (DDX5) Augments E2F1-Induced Cell Death Independent of the Tumor Suppressor p53.
Nakajima R, Zhou Y, Shirasawa M, Nishimura N, Zhao L, Fikriyanti M, Kamiya Y, Iwanaga R, Bradford AP, Shinmyozu K, Nishibuchi G, Nakayama JI, Kurayoshi K, Araki K, Ohtani K. Nakajima R, et al. Among authors: iwanaga r. Int J Mol Sci. 2024 Dec 10;25(24):13251. doi: 10.3390/ijms252413251. Int J Mol Sci. 2024. PMID: 39769018 Free PMC article.
124 results