Lehner PJ - Search Results

1

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER.

Stagg HR, Thomas M, van den Boomen D, Wiertz EJ, Drabkin HA, Gemmill RM, Lehner PJ. Stagg HR, et al. Among authors: lehner pj. J Cell Biol. 2009 Sep 7;186(5):685-92. doi: 10.1083/jcb.200906110. Epub 2009 Aug 31. J Cell Biol. 2009. PMID: 19720873 Free PMC article.

2

Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation.

Hewitt EW, Duncan L, Mufti D, Baker J, Stevenson PG, Lehner PJ. Hewitt EW, et al. Among authors: lehner pj. EMBO J. 2002 May 15;21(10):2418-29. doi: 10.1093/emboj/21.10.2418. EMBO J. 2002. PMID: 12006494 Free PMC article.

3

Recent developments in MHC-class-I-mediated antigen presentation.

Lehner PJ, Cresswell P. Lehner PJ, et al. Curr Opin Immunol. 2004 Feb;16(1):82-9. doi: 10.1016/j.coi.2003.11.012. Curr Opin Immunol. 2004. PMID: 14734114 Review.

4

Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases.

Lehner PJ, Hoer S, Dodd R, Duncan LM. Lehner PJ, et al. Immunol Rev. 2005 Oct;207:112-25. doi: 10.1111/j.0105-2896.2005.00314.x. Immunol Rev. 2005. PMID: 16181331 Review.

5

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.

Duncan LM, Piper S, Dodd RB, Saville MK, Sanderson CM, Luzio JP, Lehner PJ. Duncan LM, et al. Among authors: lehner pj. EMBO J. 2006 Apr 19;25(8):1635-45. doi: 10.1038/sj.emboj.7601056. Epub 2006 Apr 6. EMBO J. 2006. PMID: 16601694 Free PMC article.

6

MARCH-IX mediates ubiquitination and downregulation of ICAM-1.

Hoer S, Smith L, Lehner PJ. Hoer S, et al. Among authors: lehner pj. FEBS Lett. 2007 Jan 9;581(1):45-51. doi: 10.1016/j.febslet.2006.11.075. Epub 2006 Dec 8. FEBS Lett. 2007. PMID: 17174307 Free article.

7

HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.

Lubben NB, Sahlender DA, Motley AM, Lehner PJ, Benaroch P, Robinson MS. Lubben NB, et al. Among authors: lehner pj. Mol Biol Cell. 2007 Sep;18(9):3351-65. doi: 10.1091/mbc.e07-03-0218. Epub 2007 Jun 20. Mol Biol Cell. 2007. PMID: 17581864 Free PMC article.

8

Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity.

Thomas M, Boname JM, Field S, Nejentsev S, Salio M, Cerundolo V, Wills M, Lehner PJ. Thomas M, et al. Among authors: lehner pj. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1656-61. doi: 10.1073/pnas.0707883105. Epub 2008 Jan 29. Proc Natl Acad Sci U S A. 2008. PMID: 18230726 Free PMC article.

9

Natural killer cell evasion by an E3 ubiquitin ligase from Kaposi's sarcoma-associated herpesvirus.

Thomas M, Wills M, Lehner PJ. Thomas M, et al. Among authors: lehner pj. Biochem Soc Trans. 2008 Jun;36(Pt 3):459-63. doi: 10.1042/BST0360459. Biochem Soc Trans. 2008. PMID: 18481981 Review.

10

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex.

Verweij MC, Koppers-Lalic D, Loch S, Klauschies F, de la Salle H, Quinten E, Lehner PJ, Mulder A, Knittler MR, Tampé R, Koch J, Ressing ME, Wiertz EJ. Verweij MC, et al. Among authors: lehner pj. J Immunol. 2008 Oct 1;181(7):4894-907. doi: 10.4049/jimmunol.181.7.4894. J Immunol. 2008. PMID: 18802093

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