Komuro S - Search Results

1

Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.

Usui T, Mise M, Hashizume T, Yabuki M, Komuro S. Usui T, et al. Among authors: komuro s. Drug Metab Dispos. 2009 Dec;37(12):2383-92. doi: 10.1124/dmd.109.028860. Epub 2009 Aug 31. Drug Metab Dispos. 2009. PMID: 19720731

2

Characterization of substrate specificity of dog CYP1A2 using CYP1A2-deficient and wild-type dog liver microsomes.

Mise M, Hashizume T, Komuro S. Mise M, et al. Among authors: komuro s. Drug Metab Dispos. 2008 Sep;36(9):1903-8. doi: 10.1124/dmd.108.022301. Epub 2008 Jun 23. Drug Metab Dispos. 2008. PMID: 18573860

3

Prediction of the intestinal first-pass metabolism of CYP3A substrates in humans using cynomolgus monkeys.

Nishimuta H, Sato K, Mizuki Y, Yabuki M, Komuro S. Nishimuta H, et al. Among authors: komuro s. Drug Metab Dispos. 2010 Nov;38(11):1967-75. doi: 10.1124/dmd.110.034561. Epub 2010 Aug 11. Drug Metab Dispos. 2010. PMID: 20702772

4

In vitro investigation of the glutathione transferase M1 and T1 null genotypes as risk factors for troglitazone-induced liver injury.

Usui T, Hashizume T, Katsumata T, Yokoi T, Komuro S. Usui T, et al. Among authors: komuro s. Drug Metab Dispos. 2011 Jul;39(7):1303-10. doi: 10.1124/dmd.111.038661. Epub 2011 Apr 21. Drug Metab Dispos. 2011. PMID: 21511944

5

Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.

Kitamura A, Mizuno Y, Natsui K, Yabuki M, Komuro S, Kanamaru H. Kitamura A, et al. Among authors: komuro s. Biopharm Drug Dispos. 2005 Mar;26(2):59-65. doi: 10.1002/bdd.432. Biopharm Drug Dispos. 2005. PMID: 15619261

6

The new acyl-CoA cholesterol acyltransferase inhibitor SMP-797 does not interact with statins via OATP1B1 in human cryopreserved hepatocytes and oocytes expressing systems.

Kitamura A, Imai S, Yabuki M, Komuro S. Kitamura A, et al. Among authors: komuro s. Biopharm Drug Dispos. 2007 Dec;28(9):517-25. doi: 10.1002/bdd.581. Biopharm Drug Dispos. 2007. PMID: 17918775

7

Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Natsui K, Mizuno Y, Tani N, Yabuki M, Komuro S. Natsui K, et al. Among authors: komuro s. Eur J Drug Metab Pharmacokinet. 2007 Jul-Sep;32(3):131-7. doi: 10.1007/BF03190475. Eur J Drug Metab Pharmacokinet. 2007. Retraction in: Eur J Drug Metab Pharmacokinet. 2019 Dec;44(6):853. doi: 10.1007/s13318-019-00585-5 PMID: 18062405 Retracted.

8

Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes.

Natsui K, Mizuno Y, Tani N, Yabuki M, Komuro S. Natsui K, et al. Among authors: komuro s. Eur J Drug Metab Pharmacokinet. 2007 Oct-Dec;32(4):233-40. doi: 10.1007/BF03191009. Eur J Drug Metab Pharmacokinet. 2007. PMID: 18348473

9

A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes.

Sogame Y, Kitamura A, Yabuki M, Komuro S. Sogame Y, et al. Among authors: komuro s. Biopharm Drug Dispos. 2009 Nov;30(8):476-84. doi: 10.1002/bdd.684. Biopharm Drug Dispos. 2009. PMID: 19768675

10

Pharmacokinetics characterization of liposomal amphotericin B: investigation of clearance process and drug interaction potential.

Matsui S, Imai S, Yabuki M, Komuro S. Matsui S, et al. Among authors: komuro s. Arzneimittelforschung. 2009;59(9):461-70. doi: 10.1055/s-0031-1296426. Arzneimittelforschung. 2009. PMID: 19856794

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