Mowbray CE - Search Results

1

Pyrazole NNRTIs 3: optimisation of physicochemical properties.

Mowbray CE, Corbau R, Hawes M, Jones LH, Mills JE, Perros M, Selby MD, Stupple PA, Webster R, Wood A. Mowbray CE, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5603-6. doi: 10.1016/j.bmcl.2009.08.043. Epub 2009 Aug 14. Bioorg Med Chem Lett. 2009. PMID: 19717303

2

Structure-activity relationships of 1,4-dihydro-(1H,4H)-quinoxaline-2,3-diones as N-methyl-D-aspartate (glycine site) receptor antagonists. 1. Heterocyclic substituted 5-alkyl derivatives.

Fray MJ, Bull DJ, Carr CL, Gautier EC, Mowbray CE, Stobie A. Fray MJ, et al. Among authors: mowbray ce. J Med Chem. 2001 Jun 7;44(12):1951-62. doi: 10.1021/jm001124p. J Med Chem. 2001. PMID: 11384240

3

A concise and selective synthesis of novel 5-aryloxyimidazole NNRTIs.

Jones LH, Dupont T, Mowbray CE, Newman SD. Jones LH, et al. Among authors: mowbray ce. Org Lett. 2006 Apr 13;8(8):1725-7. doi: 10.1021/ol060316x. Org Lett. 2006. PMID: 16597151

4

Small, non-peptide C5a receptor antagonists: part 2.

Blagg J, Mowbray C, Pryde D, Salmon G, Fairman D, Schmid E, Beaumont K. Blagg J, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5605-8. doi: 10.1016/j.bmcl.2008.08.101. Epub 2008 Aug 31. Bioorg Med Chem Lett. 2008. PMID: 18804369

5

Small, non-peptide C5a receptor antagonists: part 1.

Blagg J, Mowbray C, Pryde DC, Salmon G, Schmid E, Fairman D, Beaumont K. Blagg J, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5601-4. doi: 10.1016/j.bmcl.2008.08.106. Epub 2008 Aug 31. Bioorg Med Chem Lett. 2008. PMID: 18809326

6

Optimization of 5-aryloxyimidazole non-nucleoside reverse transcriptase inhibitors.

Jones LH, Allan G, Corbau R, Hay D, Middleton DS, Mowbray CE, Newman SD, Perros M, Randall A, Vuong H, Webster R, Westby M, Williams D. Jones LH, et al. Among authors: mowbray ce. ChemMedChem. 2008 Nov;3(11):1756-62. doi: 10.1002/cmdc.200800183. ChemMedChem. 2008. PMID: 18855969

7

Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlays.

Jones LH, Allan G, Barba O, Burt C, Corbau R, Dupont T, Knöchel T, Irving S, Middleton DS, Mowbray CE, Perros M, Ringrose H, Swain NA, Webster R, Westby M, Phillips C. Jones LH, et al. Among authors: mowbray ce. J Med Chem. 2009 Feb 26;52(4):1219-23. doi: 10.1021/jm801322h. J Med Chem. 2009. PMID: 19175319

8

Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction.

Williams DH, Adam F, Fenwick DR, Fok-Seang J, Gardner I, Hay D, Jaiessh R, Middleton DS, Mowbray CE, Parkinson T, Perros M, Pickford C, Platts M, Randall A, Siddle D, Stephenson PT, Tran TD, Vuong H. Williams DH, et al. Among authors: mowbray ce. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5246-9. doi: 10.1016/j.bmcl.2009.06.080. Epub 2009 Jun 25. Bioorg Med Chem Lett. 2009. PMID: 19620004

9

Pyrazole NNRTIs 1: design and initial optimisation of a novel template.

Mowbray CE, Burt C, Corbau R, Perros M, Tran I, Stupple PA, Webster R, Wood A. Mowbray CE, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5599-602. doi: 10.1016/j.bmcl.2009.08.039. Epub 2009 Aug 13. Bioorg Med Chem Lett. 2009. PMID: 19709880

10

Pyrazole NNRTIs 4: selection of UK-453,061 (lersivirine) as a development candidate.

Mowbray CE, Burt C, Corbau R, Gayton S, Hawes M, Perros M, Tran I, Price DA, Quinton FJ, Selby MD, Stupple PA, Webster R, Wood A. Mowbray CE, et al. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5857-60. doi: 10.1016/j.bmcl.2009.08.080. Epub 2009 Aug 27. Bioorg Med Chem Lett. 2009. PMID: 19748778

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