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TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines.
Kuai J, Gregory B, Hill A, Pittman DD, Feldman JL, Brown T, Carito B, O'Toole M, Ramsey R, Adolfsson O, Shields KM, Dower K, Hall JP, Kurdi Y, Beech JT, Nanchahal J, Feldmann M, Foxwell BM, Brennan FM, Winkler DG, Lin LL. Kuai J, et al. Among authors: nanchahal j. Rheumatology (Oxford). 2009 Nov;48(11):1352-8. doi: 10.1093/rheumatology/kep235. Epub 2009 Aug 27. Rheumatology (Oxford). 2009. PMID: 19713442
Anti-TNF therapy: past, present and future.
Monaco C, Nanchahal J, Taylor P, Feldmann M. Monaco C, et al. Among authors: nanchahal j. Int Immunol. 2015 Jan;27(1):55-62. doi: 10.1093/intimm/dxu102. Epub 2014 Nov 19. Int Immunol. 2015. PMID: 25411043 Free PMC article. Review.
Alarmins: awaiting a clinical response.
Chan JK, Roth J, Oppenheim JJ, Tracey KJ, Vogl T, Feldmann M, Horwood N, Nanchahal J. Chan JK, et al. Among authors: nanchahal j. J Clin Invest. 2012 Aug;122(8):2711-9. doi: 10.1172/JCI62423. Epub 2012 Aug 1. J Clin Invest. 2012. PMID: 22850880 Free PMC article. Review.
Anti-TNF Therapy.
Udalova I, Monaco C, Nanchahal J, Feldmann M. Udalova I, et al. Among authors: nanchahal j. Microbiol Spectr. 2016 Aug;4(4). doi: 10.1128/microbiolspec.MCHD-0022-2015. Microbiol Spectr. 2016. PMID: 27726761 Free article. Review.
Study protocol: A multi-centre, double blind, randomised, placebo-controlled, parallel group, phase II trial (RIDD) to determine the efficacy of intra-nodular injection of anti-TNF to control disease progression in early Dupuytren's disease, with an embedded dose response study.
Nanchahal J, Ball C, Swettenham J, Dutton S, Barber V, Black J, Copsey B, Dritsaki M, Taylor P, Gray A, Feldmann M, Lamb S. Nanchahal J, et al. Wellcome Open Res. 2017 Nov 16;2:37. doi: 10.12688/wellcomeopenres.11466.2. eCollection 2017. Wellcome Open Res. 2017. PMID: 29218326 Free PMC article.
129 results