Prisinzano TE - Search Results

1

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors.

Simpson DS, Lovell KM, Lozama A, Han N, Day VW, Dersch CM, Rothman RB, Prisinzano TE. Simpson DS, et al. Among authors: prisinzano te. Org Biomol Chem. 2009 Sep 21;7(18):3748-56. doi: 10.1039/b905148a. Epub 2009 Jul 14. Org Biomol Chem. 2009. PMID: 19707679 Free PMC article.

2

Synthesis and biological activity of 8beta-substituted hydrocodone indole and hydromorphone indole derivatives.

Yu H, Prisinzano T, Dersch CM, Marcus J, Rothman RB, Jacobson AE, Rice KC. Yu H, et al. Bioorg Med Chem Lett. 2002 Jan 21;12(2):165-8. doi: 10.1016/s0960-894x(01)00689-8. Bioorg Med Chem Lett. 2002. PMID: 11755345

3

Piperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909): high affinity ligands for the dopamine transporter.

Prisinzano T, Greiner E, Johnson EM 2nd, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Prisinzano T, et al. J Med Chem. 2002 Sep 12;45(19):4371-4. doi: 10.1021/jm020264r. J Med Chem. 2002. PMID: 12213078

4

Synthesis and dopamine transporter affinity of chiral 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-hydroxypropyl)piperazines as potential cocaine abuse therapeutic agents.

Hsin LW, Prisinzano T, Wilkerson CR, Dersch CM, Horel R, Jacobson AE, Rothman RB, Rice KC. Hsin LW, et al. Bioorg Med Chem Lett. 2003 Feb 10;13(3):553-6. doi: 10.1016/s0960-894x(02)00940-x. Bioorg Med Chem Lett. 2003. PMID: 12565970

5

Further exploration of 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]piperazine (GBR 12909): role of N-aromatic, N-heteroaromatic, and 3-oxygenated N-phenylpropyl substituents on affinity for the dopamine and serotonin transporter.

Lewis D, Zhang Y, Prisinzano T, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Lewis D, et al. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1385-9. doi: 10.1016/s0960-894x(03)00108-2. Bioorg Med Chem Lett. 2003. PMID: 12657288

6

Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.

Greiner E, Prisinzano T, Johnson EM 2nd, Dersch CM, Marcus J, Partilla JS, Rothman RB, Jacobson AE, Rice KC. Greiner E, et al. J Med Chem. 2003 Apr 10;46(8):1465-9. doi: 10.1021/jm020419v. J Med Chem. 2003. PMID: 12672246

7

High-dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain.

Rothman RB, Jayanthi S, Wang X, Dersch CM, Cadet JL, Prisinzano T, Rice KC, Baumann MH. Rothman RB, et al. Synapse. 2003 Dec 1;50(3):233-9. doi: 10.1002/syn.10266. Synapse. 2003. PMID: 14515341

8

Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum.

Harding WW, Tidgewell K, Schmidt M, Shah K, Dersch CM, Snyder J, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. Harding WW, et al. Among authors: prisinzano te. Org Lett. 2005 Jul 7;7(14):3017-20. doi: 10.1021/ol0510522. Org Lett. 2005. PMID: 15987194 Free PMC article.

9

Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.

Harding WW, Tidgewell K, Byrd N, Cobb H, Dersch CM, Butelman ER, Rothman RB, Prisinzano TE. Harding WW, et al. Among authors: prisinzano te. J Med Chem. 2005 Jul 28;48(15):4765-71. doi: 10.1021/jm048963m. J Med Chem. 2005. PMID: 16033256

10

Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates.

Schmidt MD, Schmidt MS, Butelman ER, Harding WW, Tidgewell K, Murry DJ, Kreek MJ, Prisinzano TE. Schmidt MD, et al. Among authors: prisinzano te. Synapse. 2005 Dec 1;58(3):208-10. doi: 10.1002/syn.20191. Synapse. 2005. PMID: 16138318

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