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Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells.
Zeniou M, Fève M, Mameri S, Dong J, Salomé C, Chen W, El-Habr EA, Bousson F, Sy M, Obszynski J, Boh A, Villa P, Assad Kahn S, Didier B, Bagnard D, Junier MP, Chneiweiss H, Haiech J, Hibert M, Kilhoffer MC. Zeniou M, et al. Among authors: haiech j. PLoS One. 2015 Aug 13;10(8):e0134793. doi: 10.1371/journal.pone.0134793. eCollection 2015. PLoS One. 2015. PMID: 26270679 Free PMC article.
A general framework to characterize inhibitors of calmodulin: use of calmodulin inhibitors to study the interaction between calmodulin and its calmodulin binding domains.
Audran E, Dagher R, Gioria S, Tsvetkov PO, Kulikova AA, Didier B, Villa P, Makarov AA, Kilhoffer MC, Haiech J. Audran E, et al. Among authors: haiech j. Biochim Biophys Acta. 2013 Jul;1833(7):1720-31. doi: 10.1016/j.bbamcr.2013.01.008. Epub 2013 Jan 17. Biochim Biophys Acta. 2013. PMID: 23333870 Free article.
Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.
Regenass P, Abboud D, Daubeuf F, Lehalle C, Gizzi P, Riché S, Hachet-Haas M, Rohmer F, Gasparik V, Boeglin D, Haiech J, Knehans T, Rognan D, Heissler D, Marsol C, Villa P, Galzi JL, Hibert M, Frossard N, Bonnet D. Regenass P, et al. Among authors: haiech j. J Med Chem. 2018 Sep 13;61(17):7671-7686. doi: 10.1021/acs.jmedchem.8b00657. Epub 2018 Aug 28. J Med Chem. 2018. PMID: 30106292
WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3- cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling.
Chen W, Zebaze LN, Dong J, Chézeau L, Inquimbert P, Hugel S, Niu S, Bihel F, Boutant E, Réal E, Villa P, Junier MP, Chneiweiss H, Hibert M, Haiech J, Kilhoffer MC, Zeniou M. Chen W, et al. Among authors: haiech j. Oncotarget. 2018 Jun 5;9(43):27197-27219. doi: 10.18632/oncotarget.25509. eCollection 2018 Jun 5. Oncotarget. 2018. PMID: 29930759 Free PMC article.
166 results