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Effect of a novel NOP receptor agonist (SCH 225288) on guinea pig irritant-evoked, feline mechanically induced and canine infectious tracheobronchitis cough.
McLeod RL, Tulshian DB, Ho GD, Fernandez X, Bolser DC, Parra LE, Zimmer JC, Erickson CH, Fawzi AB, Jayappa H, Lehr C, Erskine J, Smith-Torhan A, Zhang H, Hey JA. McLeod RL, et al. Among authors: zhang h. Pharmacology. 2009;84(3):153-61. doi: 10.1159/000235601. Epub 2009 Aug 20. Pharmacology. 2009. PMID: 19696521
Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.
McLeod RL, Jia Y, Fernandez X, Parra LE, Wang X, Tulshian DB, Kiselgof EJ, Tan Z, Fawzi AB, Smith-Torhan A, Zhang H, Hey JA. McLeod RL, et al. Among authors: zhang h. Pharmacology. 2004 Jul;71(3):143-9. doi: 10.1159/000077448. Pharmacology. 2004. PMID: 15161996
The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).
Varty GB, Lu SX, Morgan CA, Cohen-Williams ME, Hodgson RA, Smith-Torhan A, Zhang H, Fawzi AB, Graziano MP, Ho GD, Matasi J, Tulshian D, Coffin VL, Carey GJ. Varty GB, et al. Among authors: zhang h. J Pharmacol Exp Ther. 2008 Aug;326(2):672-82. doi: 10.1124/jpet.108.136937. Epub 2008 May 20. J Pharmacol Exp Ther. 2008. PMID: 18492950
The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety.
Ho GD, Anthes J, Bercovici A, Caldwell JP, Cheng KC, Cui X, Fawzi A, Fernandez X, Greenlee WJ, Hey J, Korfmacher W, Lu SX, McLeod RL, Ng F, Torhan AS, Tan Z, Tulshian D, Varty GB, Xu X, Zhang H. Ho GD, et al. Among authors: zhang h. Bioorg Med Chem Lett. 2009 May 1;19(9):2519-23. doi: 10.1016/j.bmcl.2009.03.031. Epub 2009 Mar 14. Bioorg Med Chem Lett. 2009. PMID: 19339177
129,731 results
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