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HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice.
Atkins KM, Thomas L, Youker RT, Harriff MJ, Pissani F, You H, Thomas G. Atkins KM, et al. Among authors: thomas g, thomas l. J Biol Chem. 2008 Apr 25;283(17):11772-84. doi: 10.1074/jbc.M707572200. Epub 2008 Feb 22. J Biol Chem. 2008. PMID: 18296443 Free PMC article.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2).
Werneburg NW, Bronk SF, Guicciardi ME, Thomas L, Dikeakos JD, Thomas G, Gores GJ. Werneburg NW, et al. Among authors: thomas g, thomas l. J Biol Chem. 2012 Jul 13;287(29):24427-37. doi: 10.1074/jbc.M112.342238. Epub 2012 May 29. J Biol Chem. 2012. PMID: 22645134 Free PMC article.
Cellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity.
Guicciardi ME, Werneburg NW, Bronk SF, Franke A, Yagita H, Thomas G, Gores GJ. Guicciardi ME, et al. Among authors: thomas g. PLoS One. 2014 Mar 14;9(3):e92124. doi: 10.1371/journal.pone.0092124. eCollection 2014. PLoS One. 2014. PMID: 24633224 Free PMC article.
PACS-2 functions in colorectal cancer.
Kveiborg M, Thomas G. Kveiborg M, et al. Among authors: thomas g. Aging (Albany NY). 2018 Jun 22;10(6):1190-1191. doi: 10.18632/aging.101489. Aging (Albany NY). 2018. PMID: 29936496 Free PMC article. No abstract available.
The subcellular distribution of calnexin is mediated by PACS-2.
Myhill N, Lynes EM, Nanji JA, Blagoveshchenskaya AD, Fei H, Carmine Simmen K, Cooper TJ, Thomas G, Simmen T. Myhill N, et al. Among authors: thomas g. Mol Biol Cell. 2008 Jul;19(7):2777-88. doi: 10.1091/mbc.e07-10-0995. Epub 2008 Apr 16. Mol Biol Cell. 2008. PMID: 18417615 Free PMC article.
6,160 results