Gotthardt M - Search Results

1

Altered contractility of skeletal muscle in mice deficient in titin's M-band region.

Ottenheijm CA, Hidalgo C, Rost K, Gotthardt M, Granzier H. Ottenheijm CA, et al. Among authors: gotthardt m. J Mol Biol. 2009 Oct 16;393(1):10-26. doi: 10.1016/j.jmb.2009.08.009. Epub 2009 Aug 13. J Mol Biol. 2009. PMID: 19683008 Free PMC article.

2

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system.

Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S. Bang ML, et al. Among authors: gotthardt m. Circ Res. 2001 Nov 23;89(11):1065-72. doi: 10.1161/hh2301.100981. Circ Res. 2001. PMID: 11717165

3

Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.

Gotthardt M, Hammer RE, Hübner N, Monti J, Witt CC, McNabb M, Richardson JA, Granzier H, Labeit S, Herz J. Gotthardt M, et al. J Biol Chem. 2003 Feb 21;278(8):6059-65. doi: 10.1074/jbc.M211723200. Epub 2002 Dec 2. J Biol Chem. 2003. PMID: 12464612 Free article.

4

Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.

Witt CC, Ono Y, Puschmann E, McNabb M, Wu Y, Gotthardt M, Witt SH, Haak M, Labeit D, Gregorio CC, Sorimachi H, Granzier H, Labeit S. Witt CC, et al. Among authors: gotthardt m. J Mol Biol. 2004 Feb 6;336(1):145-54. doi: 10.1016/j.jmb.2003.12.021. J Mol Biol. 2004. PMID: 14741210

5

Adaptations in titin's spring elements in normal and cardiomyopathic hearts.

Granzier H, Labeit D, Wu Y, Witt C, Watanabe K, Lahmers S, Gotthardt M, Labeit S. Granzier H, et al. Among authors: gotthardt m. Adv Exp Med Biol. 2003;538:517-30; discussion 530-1. doi: 10.1007/978-1-4419-9029-7_46. Adv Exp Med Biol. 2003. PMID: 15098695

6

Muscle atrophy in titin M-line deficient mice.

Peng J, Raddatz K, Labeit S, Granzier H, Gotthardt M. Peng J, et al. Among authors: gotthardt m. J Muscle Res Cell Motil. 2005;26(6-8):381-8. doi: 10.1007/s10974-005-9020-y. J Muscle Res Cell Motil. 2005. PMID: 16470336

7

M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere.

Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M. Weinert S, et al. Among authors: gotthardt m. J Cell Biol. 2006 May 22;173(4):559-70. doi: 10.1083/jcb.200601014. Epub 2006 May 15. J Cell Biol. 2006. PMID: 16702235 Free PMC article.

8

Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region.

Peng J, Raddatz K, Molkentin JD, Wu Y, Labeit S, Granzier H, Gotthardt M. Peng J, et al. Among authors: gotthardt m. Circulation. 2007 Feb 13;115(6):743-51. doi: 10.1161/CIRCULATIONAHA.106.645499. Epub 2007 Jan 29. Circulation. 2007. PMID: 17261657

9

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.

Radke MH, Peng J, Wu Y, McNabb M, Nelson OL, Granzier H, Gotthardt M. Radke MH, et al. Among authors: gotthardt m. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3444-9. doi: 10.1073/pnas.0608543104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360664 Free PMC article.

10

Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle.

Granzier H, Radke M, Royal J, Wu Y, Irving TC, Gotthardt M, Labeit S. Granzier H, et al. Among authors: gotthardt m. Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R557-67. doi: 10.1152/ajpregu.00001.2007. Epub 2007 May 23. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17522126 Free article.

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