Bagg EA - Search Results

1

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.

Church C, Lee S, Bagg EA, McTaggart JS, Deacon R, Gerken T, Lee A, Moir L, Mecinović J, Quwailid MM, Schofield CJ, Ashcroft FM, Cox RD. Church C, et al. Among authors: bagg ea. PLoS Genet. 2009 Aug;5(8):e1000599. doi: 10.1371/journal.pgen.1000599. Epub 2009 Aug 14. PLoS Genet. 2009. PMID: 19680540 Free PMC article.

2

Structural basis for inhibition of the fat mass and obesity associated protein (FTO).

Aik W, Demetriades M, Hamdan MK, Bagg EA, Yeoh KK, Lejeune C, Zhang Z, McDonough MA, Schofield CJ. Aik W, et al. Among authors: bagg ea. J Med Chem. 2013 May 9;56(9):3680-8. doi: 10.1021/jm400193d. Epub 2013 Apr 23. J Med Chem. 2013. PMID: 23547775

3

Mechanistic studies on the application of DNA aptamers as inhibitors of 2-oxoglutarate-dependent oxygenases.

Krylova SM, Koshkin V, Bagg E, Schofield CJ, Krylov SN. Krylova SM, et al. J Med Chem. 2012 Apr 12;55(7):3546-52. doi: 10.1021/jm300243h. Epub 2012 Apr 3. J Med Chem. 2012. PMID: 22471443 Free PMC article.

4

Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases.

Flashman E, Bagg EA, Chowdhury R, Mecinović J, Loenarz C, McDonough MA, Hewitson KS, Schofield CJ. Flashman E, et al. Among authors: bagg ea. J Biol Chem. 2008 Feb 15;283(7):3808-15. doi: 10.1074/jbc.M707411200. Epub 2007 Dec 5. J Biol Chem. 2008. PMID: 18063574 Free article.

5

Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase.

Woon EC, Demetriades M, Bagg EA, Aik W, Krylova SM, Ma JH, Chan M, Walport LJ, Wegman DW, Dack KN, McDonough MA, Krylov SN, Schofield CJ. Woon EC, et al. Among authors: bagg ea. J Med Chem. 2012 Mar 8;55(5):2173-84. doi: 10.1021/jm201417e. Epub 2012 Feb 22. J Med Chem. 2012. PMID: 22263962

6

DNA aptamers for as analytical tools for the quantitative analysis of DNA-dealkylating enzymes.

Krylova SM, Karkhanina AA, Musheev MU, Bagg EA, Schofield CJ, Krylov SN. Krylova SM, et al. Among authors: bagg ea. Anal Biochem. 2011 Jul 15;414(2):261-5. doi: 10.1016/j.ab.2011.03.010. Epub 2011 Mar 12. Anal Biochem. 2011. PMID: 21402046

7

Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6.

Mantri M, Krojer T, Bagg EA, Webby CJ, Butler DS, Kochan G, Kavanagh KL, Oppermann U, McDonough MA, Schofield CJ. Mantri M, et al. Among authors: bagg ea. J Mol Biol. 2010 Aug 13;401(2):211-22. J Mol Biol. 2010. PMID: 20684070

8

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.

Chowdhury R, Yeoh KK, Tian YM, Hillringhaus L, Bagg EA, Rose NR, Leung IK, Li XS, Woon EC, Yang M, McDonough MA, King ON, Clifton IJ, Klose RJ, Claridge TD, Ratcliffe PJ, Schofield CJ, Kawamura A. Chowdhury R, et al. Among authors: bagg ea. EMBO Rep. 2011 May;12(5):463-9. doi: 10.1038/embor.2011.43. Epub 2011 Apr 1. EMBO Rep. 2011. PMID: 21460794 Free PMC article.

9

Emulsion PCR significantly improves nonequilibrium capillary electrophoresis of equilibrium mixtures-based aptamer selection: allowing for efficient and rapid selection of aptamer to unmodified ABH2 protein.

Yufa R, Krylova SM, Bruce C, Bagg EA, Schofield CJ, Krylov SN. Yufa R, et al. Among authors: bagg ea. Anal Chem. 2015 Jan 20;87(2):1411-9. doi: 10.1021/ac5044187. Epub 2014 Dec 29. Anal Chem. 2015. PMID: 25495441

10

Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6.

Mantri M, Krojer T, Bagg EA, Webby CA, Butler DS, Kochan G, Kavanagh KL, Oppermann U, McDonough MA, Schofield CJ. Mantri M, et al. Among authors: bagg ea. J Mol Biol. 2010 May 31. doi: 10.1016/j.jmb.2010.05.054. Online ahead of print. J Mol Biol. 2010. PMID: 20685276

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