El-Haou S - Search Results

1

Rheumatic heart disease screening by echocardiography: the inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease.

Marijon E, Celermajer DS, Tafflet M, El-Haou S, Jani DN, Ferreira B, Mocumbi AO, Paquet C, Sidi D, Jouven X. Marijon E, et al. Among authors: el haou s. Circulation. 2009 Aug 25;120(8):663-8. doi: 10.1161/CIRCULATIONAHA.109.849190. Epub 2009 Aug 10. Circulation. 2009. PMID: 19667239 Clinical Trial.

2

Kv4 potassium channels form a tripartite complex with the anchoring protein SAP97 and CaMKII in cardiac myocytes.

El-Haou S, Balse E, Neyroud N, Dilanian G, Gavillet B, Abriel H, Coulombe A, Jeromin A, Hatem SN. El-Haou S, et al. Circ Res. 2009 Mar 27;104(6):758-69. doi: 10.1161/CIRCRESAHA.108.191007. Epub 2009 Feb 12. Circ Res. 2009. PMID: 19213956

3

The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes.

Abi-Char J, El-Haou S, Balse E, Neyroud N, Vranckx R, Coulombe A, Hatem SN. Abi-Char J, et al. Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1851-61. doi: 10.1152/ajpheart.01045.2007. Epub 2008 Feb 1. Am J Physiol Heart Circ Physiol. 2008. PMID: 18245566 Free article.

4

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes.

Petitprez S, Zmoos AF, Ogrodnik J, Balse E, Raad N, El-Haou S, Albesa M, Bittihn P, Luther S, Lehnart SE, Hatem SN, Coulombe A, Abriel H. Petitprez S, et al. Among authors: el haou s. Circ Res. 2011 Feb 4;108(3):294-304. doi: 10.1161/CIRCRESAHA.110.228312. Epub 2010 Dec 16. Circ Res. 2011. PMID: 21164104

5

Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes.

Balse E, El-Haou S, Dillanian G, Dauphin A, Eldstrom J, Fedida D, Coulombe A, Hatem SN. Balse E, et al. Among authors: el haou s. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14681-6. doi: 10.1073/pnas.0902809106. Epub 2009 Aug 17. Proc Natl Acad Sci U S A. 2009. PMID: 19706553 Free PMC article.

6

Activation of glibenclamide-sensitive ATP-sensitive K+ channels during β-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia.

Kim SJ, Zhang H, Khaliulin I, Choisy SC, Bond R, Lin H, El Haou S, Milnes JT, Hancox JC, Suleiman MS, James AF. Kim SJ, et al. Among authors: el haou s. Circ Arrhythm Electrophysiol. 2012 Dec;5(6):1184-92. doi: 10.1161/CIRCEP.112.975425. Epub 2012 Nov 16. Circ Arrhythm Electrophysiol. 2012. PMID: 23159416

7

Novel K+ Channel Targets in Atrial Fibrillation Drug Development--Where Are We?

El-Haou S, Ford JW, Milnes JT. El-Haou S, et al. J Cardiovasc Pharmacol. 2015 Nov;66(5):412-31. doi: 10.1097/FJC.0000000000000277. J Cardiovasc Pharmacol. 2015. PMID: 25978691 Review.

8

The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation.

Ford J, Milnes J, El Haou S, Wettwer E, Loose S, Matschke K, Tyl B, Round P, Ravens U. Ford J, et al. Among authors: el haou s. Heart Rhythm. 2016 Feb;13(2):555-64. doi: 10.1016/j.hrthm.2015.10.003. Epub 2015 Oct 13. Heart Rhythm. 2016. PMID: 26455450 Free PMC article. Clinical Trial.

9

Effect of selective I_K,ACh inhibition by XAF-1407 in an equine model of tachypacing-induced persistent atrial fibrillation.

Fenner MF, Carstensen H, Dalgas Nissen S, Melis Hesselkilde E, Scott Lunddahl C, Adler Hess Jensen M, Loft-Andersen AV, Sattler SM, Platonov P, El-Haou S, Jackson C, Tang R, Kirby R, Ford J, Schotten U, Milnes J, Svane Sørensen U, Jespersen T, Buhl R. Fenner MF, et al. Among authors: el haou s. Br J Pharmacol. 2020 Aug;177(16):3778-3794. doi: 10.1111/bph.15100. Epub 2020 Jun 24. Br J Pharmacol. 2020. PMID: 32436234 Free PMC article.

10

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.

Devalla HD, Schwach V, Ford JW, Milnes JT, El-Haou S, Jackson C, Gkatzis K, Elliott DA, Chuva de Sousa Lopes SM, Mummery CL, Verkerk AO, Passier R. Devalla HD, et al. Among authors: el haou s. EMBO Mol Med. 2015 Apr;7(4):394-410. doi: 10.15252/emmm.201404757. EMBO Mol Med. 2015. PMID: 25700171 Free PMC article.

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