Alexander CM - Search Results

1

Wnt signaling can substitute for estrogen to induce division of ERalpha-positive cells in a mouse mammary tumor model.

Mastroianni M, Kim S, Kim YC, Esch A, Wagner C, Alexander CM. Mastroianni M, et al. Among authors: alexander cm. Cancer Lett. 2010 Mar 1;289(1):23-31. doi: 10.1016/j.canlet.2009.07.012. Epub 2009 Aug 8. Cancer Lett. 2010. PMID: 19665836 Free PMC article.

2

Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation.

Liu BY, Kim YC, Leatherberry V, Cowin P, Alexander CM. Liu BY, et al. Among authors: alexander cm. Oncogene. 2003 Dec 18;22(58):9243-53. doi: 10.1038/sj.onc.1207217. Oncogene. 2003. PMID: 14681683

3

The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells.

Liu BY, McDermott SP, Khwaja SS, Alexander CM. Liu BY, et al. Among authors: alexander cm. Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4158-63. doi: 10.1073/pnas.0400699101. Epub 2004 Mar 12. Proc Natl Acad Sci U S A. 2004. PMID: 15020770 Free PMC article.

4

Mammary stem and progenitor cells: tumour precursors?

Paguirigan A, Beebe DJ, Liu B, Alexander C. Paguirigan A, et al. Eur J Cancer. 2006 Jun;42(9):1225-36. doi: 10.1016/j.ejca.2006.01.048. Epub 2006 May 11. Eur J Cancer. 2006. PMID: 16697180 Review.

5

Wnt1 expression induces short-range and long-range cell recruitments that modify mammary tumor development and are not induced by a cell-autonomous beta-catenin effector.

Kim YC, Clark RJ, Ranheim EA, Alexander CM. Kim YC, et al. Among authors: alexander cm. Cancer Res. 2008 Dec 15;68(24):10145-53. doi: 10.1158/0008-5472.CAN-08-2992. Cancer Res. 2008. PMID: 19074881 Free PMC article.

6

The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage.

Badders NM, Goel S, Clark RJ, Klos KS, Kim S, Bafico A, Lindvall C, Williams BO, Alexander CM. Badders NM, et al. Among authors: alexander cm. PLoS One. 2009 Aug 12;4(8):e6594. doi: 10.1371/journal.pone.0006594. PLoS One. 2009. PMID: 19672307 Free PMC article.

7

Wnt4 is not sufficient to induce lobuloalveolar mammary development.

Kim YC, Clark RJ, Pelegri F, Alexander CM. Kim YC, et al. Among authors: alexander cm. BMC Dev Biol. 2009 Oct 30;9:55. doi: 10.1186/1471-213X-9-55. BMC Dev Biol. 2009. PMID: 19878558 Free PMC article.

8

Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept.

Kim S, Goel S, Alexander CM. Kim S, et al. Among authors: alexander cm. PLoS One. 2011 Apr 26;6(4):e19310. doi: 10.1371/journal.pone.0019310. PLoS One. 2011. PMID: 21541292 Free PMC article.

9

A phenotypic mouse model of basaloid breast tumors.

Kim S, Roopra A, Alexander CM. Kim S, et al. Among authors: alexander cm. PLoS One. 2012;7(2):e30979. doi: 10.1371/journal.pone.0030979. Epub 2012 Feb 9. PLoS One. 2012. PMID: 22347416 Free PMC article.

10

Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.

Goel S, Chin EN, Fakhraldeen SA, Berry SM, Beebe DJ, Alexander CM. Goel S, et al. Among authors: alexander cm. J Biol Chem. 2012 May 11;287(20):16454-66. doi: 10.1074/jbc.M112.362137. Epub 2012 Mar 20. J Biol Chem. 2012. PMID: 22433869 Free PMC article.

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