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Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin.
Song L, Zhang Y, Yun NE, Poussard AL, Smith JN, Smith JK, Borisevich V, Linde JJ, Zacks MA, Li H, Kavita U, Reiserova L, Liu X, Dumuren K, Balasubramanian B, Weaver B, Parent J, Umlauf S, Liu G, Huleatt J, Tussey L, Paessler S. Song L, et al. Vaccine. 2009 Sep 25;27(42):5875-84. doi: 10.1016/j.vaccine.2009.07.060. Epub 2009 Aug 3. Vaccine. 2009. PMID: 19654064 Free PMC article.
Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin.
Huleatt JW, Nakaar V, Desai P, Huang Y, Hewitt D, Jacobs A, Tang J, McDonald W, Song L, Evans RK, Umlauf S, Tussey L, Powell TJ. Huleatt JW, et al. Among authors: song l. Vaccine. 2008 Jan 10;26(2):201-14. doi: 10.1016/j.vaccine.2007.10.062. Epub 2007 Nov 20. Vaccine. 2008. PMID: 18063235
Immunogenicity and efficacy of flagellin-envelope fusion dengue vaccines in mice and monkeys.
Liu G, Song L, Beasley DW, Putnak R, Parent J, Misczak J, Li H, Reiserova L, Liu X, Tian H, Liu W, Labonte D, Duan L, Kim Y, Travalent L, Wigington D, Weaver B, Tussey L. Liu G, et al. Among authors: song l. Clin Vaccine Immunol. 2015 May;22(5):516-25. doi: 10.1128/CVI.00770-14. Epub 2015 Mar 11. Clin Vaccine Immunol. 2015. PMID: 25761459 Free PMC article.
Efficacious recombinant influenza vaccines produced by high yield bacterial expression: a solution to global pandemic and seasonal needs.
Song L, Nakaar V, Kavita U, Price A, Huleatt J, Tang J, Jacobs A, Liu G, Huang Y, Desai P, Maksymiuk G, Takahashi V, Umlauf S, Reiserova L, Bell R, Li H, Zhang Y, McDonald WF, Powell TJ, Tussey L. Song L, et al. PLoS One. 2008 May 21;3(5):e2257. doi: 10.1371/journal.pone.0002257. PLoS One. 2008. PMID: 18493310 Free PMC article.
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