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Page 1
Defining the mechanism of polymerization in the serpinopathies.
Ekeowa UI, Freeke J, Miranda E, Gooptu B, Bush MF, Pérez J, Teckman J, Robinson CV, Lomas DA. Ekeowa UI, et al. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17146-51. doi: 10.1073/pnas.1004785107. Epub 2010 Sep 20. Proc Natl Acad Sci U S A. 2010. PMID: 20855577 Free PMC article.
α(1)-antitrypsin deficiency and inflammation.
Ekeowa UI, Marciniak SJ, Lomas DA. Ekeowa UI, et al. Expert Rev Clin Immunol. 2011 Mar;7(2):243-52. doi: 10.1586/eci.10.95. Expert Rev Clin Immunol. 2011. PMID: 21426261 Review.
ANCA-associated vasculitis is linked to carriage of the Z allele of α₁ antitrypsin and its polymers.
Morris H, Morgan MD, Wood AM, Smith SW, Ekeowa UI, Herrmann K, Holle JU, Guillevin L, Lomas DA, Perez J, Pusey CD, Salama AD, Stockley R, Wieczorek S, McKnight AJ, Maxwell AP, Miranda E, Williams J, Savage CO, Harper L. Morris H, et al. Among authors: ekeowa ui. Ann Rheum Dis. 2011 Oct;70(10):1851-6. doi: 10.1136/ard.2011.153569. Epub 2011 Aug 5. Ann Rheum Dis. 2011. PMID: 21821620
The serpinopathies studying serpin polymerization in vivo.
Irving JA, Ekeowa UI, Belorgey D, Haq I, Gooptu B, Miranda E, Pérez J, Roussel BD, Ordóñez A, Dalton LE, Thomas SE, Marciniak SJ, Parfrey H, Chilvers ER, Teckman JH, Alam S, Mahadeva R, Rashid ST, Vallier L, Lomas DA. Irving JA, et al. Among authors: ekeowa ui. Methods Enzymol. 2011;501:421-66. doi: 10.1016/B978-0-12-385950-1.00018-3. Methods Enzymol. 2011. PMID: 22078544
Characterisation of serpin polymers in vitro and in vivo.
Belorgey D, Irving JA, Ekeowa UI, Freeke J, Roussel BD, Miranda E, Pérez J, Robinson CV, Marciniak SJ, Crowther DC, Michel CH, Lomas DA. Belorgey D, et al. Among authors: ekeowa ui. Methods. 2011 Mar;53(3):255-66. doi: 10.1016/j.ymeth.2010.11.008. Epub 2010 Nov 27. Methods. 2011. PMID: 21115126 Review.
15 results