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ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency.
Sauer AV, Mrak E, Hernandez RJ, Zacchi E, Cavani F, Casiraghi M, Grunebaum E, Roifman CM, Cervi MC, Ambrosi A, Carlucci F, Roncarolo MG, Villa A, Rubinacci A, Aiuti A. Sauer AV, et al. Among authors: grunebaum e. Blood. 2009 Oct 8;114(15):3216-26. doi: 10.1182/blood-2009-03-209221. Epub 2009 Jul 24. Blood. 2009. PMID: 19633200 Free article. Clinical Trial.
Signal-transduction defects in T cells.
Grunebaum E, Roifman CM. Grunebaum E, et al. Clin Rev Allergy Immunol. 2001 Feb;20(1):27-42. doi: 10.1385/CRIAI:20:1:27. Clin Rev Allergy Immunol. 2001. PMID: 11269226 Review.
127 results