Fang Z - Search Results

1

Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies.

Zhan P, Liu X, Li Z, Fang Z, Li Z, Wang D, Pannecouque C, Clercq ED. Zhan P, et al. Among authors: fang z. Bioorg Med Chem. 2009 Aug 15;17(16):5920-7. doi: 10.1016/j.bmc.2009.07.004. Epub 2009 Jul 7. Bioorg Med Chem. 2009. PMID: 19620009

2

Design, synthesis, and neurochemical evaluation of 5-(3-alkyl-1,2,4- oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists.

Dunbar PG, Durant GJ, Fang Z, Abuh YF, el-Assadi AA, Ngur DO, Periyasamy S, Hoss WP, Messer WS Jr. Dunbar PG, et al. Among authors: fang z. J Med Chem. 1993 Apr 2;36(7):842-7. doi: 10.1021/jm00059a008. J Med Chem. 1993. PMID: 8464038

3

Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists.

Messer WS Jr, Abuh YF, Liu Y, Periyasamy S, Ngur DO, Edgar MA, El-Assadi AA, Sbeih S, Dunbar PG, Roknich S, Rho T, Fang Z, Ojo B, Zhang H, Huzl JJ 3rd, Nagy PI. Messer WS Jr, et al. Among authors: fang z. J Med Chem. 1997 Apr 11;40(8):1230-46. doi: 10.1021/jm960467d. J Med Chem. 1997. PMID: 9111297

4

Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Zhan P, Liu X, Fang Z, Li Z, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: fang z. Eur J Med Chem. 2009 Nov;44(11):4648-53. doi: 10.1016/j.ejmech.2009.06.037. Epub 2009 Jul 4. Eur J Med Chem. 2009. PMID: 19628308

5

Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Zhan P, Liu X, Zhu J, Fang Z, Li Z, Pannecouque C, Clercq ED. Zhan P, et al. Among authors: fang z. Bioorg Med Chem. 2009 Aug 15;17(16):5775-81. doi: 10.1016/j.bmc.2009.07.028. Epub 2009 Jul 18. Bioorg Med Chem. 2009. PMID: 19643613

6

1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation.

Zhan P, Liu X, Fang Z, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: fang z. Bioorg Med Chem. 2009 Sep 1;17(17):6374-9. doi: 10.1016/j.bmc.2009.07.027. Epub 2009 Jul 18. Bioorg Med Chem. 2009. PMID: 19647440

7

1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors.

Zhan P, Liu XY, Li ZY, Fang ZJ, Pannecouque C, De Clercq E. Zhan P, et al. Chem Biodivers. 2010 Jul;7(7):1717-27. doi: 10.1002/cbdv.200900197. Chem Biodivers. 2010. PMID: 20658659

8

HIV-1 NNRTIs: structural diversity, pharmacophore similarity, and implications for drug design.

Zhan P, Chen X, Li D, Fang Z, De Clercq E, Liu X. Zhan P, et al. Among authors: fang z. Med Res Rev. 2013 Jun;33 Suppl 1:E1-72. doi: 10.1002/med.20241. Epub 2011 Apr 26. Med Res Rev. 2013. PMID: 21523792 Review.

9

Recent advances in the discovery and development of novel HIV-1 NNRTI platforms (Part II): 2009-2013 update.

Song Y, Fang Z, Zhan P, Liu X. Song Y, et al. Among authors: fang z. Curr Med Chem. 2014;21(3):329-55. doi: 10.2174/09298673113206660298. Curr Med Chem. 2014. PMID: 24164196 Review.

10

Conformational restriction: an effective tactic in 'follow-on'-based drug discovery.

Fang Z, Song Y, Zhan P, Zhang Q, Liu X. Fang Z, et al. Future Med Chem. 2014 May;6(8):885-901. doi: 10.4155/fmc.14.50. Future Med Chem. 2014. PMID: 24962281 Review.

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