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A framework to assess the translation of safety pharmacology data to humans.
Valentin JP, Bialecki R, Ewart L, Hammond T, Leishmann D, Lindgren S, Martinez V, Pollard C, Redfern W, Wallis R. Valentin JP, et al. Among authors: pollard c. J Pharmacol Toxicol Methods. 2009 Sep-Oct;60(2):152-8. doi: 10.1016/j.vascn.2009.05.011. Epub 2009 Jul 17. J Pharmacol Toxicol Methods. 2009. PMID: 19616110
Safety pharmacology--a progressive approach.
Redfern WS, Wakefield ID, Prior H, Pollard CE, Hammond TG, Valentin JP. Redfern WS, et al. Fundam Clin Pharmacol. 2002 Jun;16(3):161-73. doi: 10.1046/j.1472-8206.2002.00098.x. Fundam Clin Pharmacol. 2002. PMID: 12165064
The application of in vitro methods to safety pharmacology.
Wakefield ID, Pollard C, Redfern WS, Hammond TG, Valentin JP. Wakefield ID, et al. Among authors: pollard c. Fundam Clin Pharmacol. 2002 Jun;16(3):209-18. doi: 10.1046/j.1472-8206.2002.00099.x. Fundam Clin Pharmacol. 2002. PMID: 12165068 Review.
Use of in vitro methods to predict QT prolongation.
Hammond TG, Pollard CE. Hammond TG, et al. Among authors: pollard ce. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):446-50. doi: 10.1016/j.taap.2005.03.022. Toxicol Appl Pharmacol. 2005. PMID: 16023163 Review.
Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks HT.
Bridgland-Taylor MH, Hargreaves AC, Easter A, Orme A, Henthorn DC, Ding M, Davis AM, Small BG, Heapy CG, Abi-Gerges N, Persson F, Jacobson I, Sullivan M, Albertson N, Hammond TG, Sullivan E, Valentin JP, Pollard CE. Bridgland-Taylor MH, et al. Among authors: pollard ce. J Pharmacol Toxicol Methods. 2006 Sep-Oct;54(2):189-99. doi: 10.1016/j.vascn.2006.02.003. Epub 2006 Mar 6. J Pharmacol Toxicol Methods. 2006. PMID: 16563806
800 results