Han X - Search Results

1

Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluorocarboxylates in rats.

Yang CH, Glover KP, Han X. Yang CH, et al. Among authors: han x. Toxicol Lett. 2009 Oct 28;190(2):163-71. doi: 10.1016/j.toxlet.2009.07.011. Epub 2009 Jul 16. Toxicol Lett. 2009. PMID: 19616083

2

Uptake of perfluorooctanoate in freshly isolated hepatocytes from male and female rats.

Han X, Yang CH, Snajdr SI, Nabb DL, Mingoia RT. Han X, et al. Toxicol Lett. 2008 Sep 26;181(2):81-6. doi: 10.1016/j.toxlet.2008.07.002. Epub 2008 Jul 10. Toxicol Lett. 2008. PMID: 18662756

3

Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates.

Yang CH, Glover KP, Han X. Yang CH, et al. Among authors: han x. Toxicol Sci. 2010 Oct;117(2):294-302. doi: 10.1093/toxsci/kfq219. Epub 2010 Jul 16. Toxicol Sci. 2010. PMID: 20639259

4

Protein kinase C-activating tumor promoters modulate the DNA damage response in UVC-irradiated TK6 cells.

Glover KP, Markell LK, Donner EM, Han X. Glover KP, et al. Among authors: han x. Toxicol Lett. 2014 Aug 17;229(1):210-9. doi: 10.1016/j.toxlet.2014.06.030. Epub 2014 Jun 21. Toxicol Lett. 2014. PMID: 24960060

5

Liver microsomes and S9 from rainbow trout (Oncorhynchus mykiss): comparison of basal-level enzyme activities with rat and determination of xenobiotic intrinsic clearance in support of bioaccumulation assessment.

Han X, Nabb DL, Yang CH, Snajdr SI, Mingoia RT. Han X, et al. Environ Toxicol Chem. 2009 Mar;28(3):481-8. doi: 10.1897/08-269.1. Epub 2008 Oct 20. Environ Toxicol Chem. 2009. PMID: 18937539

6

Cryopreserved hepatocytes from rainbow trout (Oncorhynchus mykiss): a validation study to support their application in bioaccumulation assessment.

Mingoia RT, Glover KP, Nabb DL, Yang CH, Snajdr SI, Han X. Mingoia RT, et al. Among authors: han x. Environ Sci Technol. 2010 Apr 15;44(8):3052-8. doi: 10.1021/es903909g. Environ Sci Technol. 2010. PMID: 20196591

7

Comparison of basal level metabolic enzyme activities of freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) and rat.

Nabb DL, Mingoia RT, Yang CH, Han X. Nabb DL, et al. Among authors: han x. Aquat Toxicol. 2006 Oct 25;80(1):52-9. doi: 10.1016/j.aquatox.2006.07.012. Epub 2006 Jul 22. Aquat Toxicol. 2006. PMID: 16935359

8

Primary culture of rat hepatocytes in 96-well plates: effects of extracellular matrix configuration on cytochrome P450 enzyme activity and inducibility, and its application in in vitro cytotoxicity screening.

Mingoia RT, Nabb DL, Yang CH, Han X. Mingoia RT, et al. Among authors: han x. Toxicol In Vitro. 2007 Feb;21(1):165-73. doi: 10.1016/j.tiv.2006.10.012. Epub 2006 Oct 28. Toxicol In Vitro. 2007. PMID: 17141466

9

Xenobiotic intrinsic clearance in freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss): determination of trout hepatocellularity, optimization of cell concentrations and comparison of serum and serum-free incubations.

Han X, Mingoia RT, Nabb DL, Yang CH, Snajdr SI, Hoke RA. Han X, et al. Aquat Toxicol. 2008 Aug 11;89(1):11-7. doi: 10.1016/j.aquatox.2008.05.010. Epub 2008 May 23. Aquat Toxicol. 2008. PMID: 18599132

In vitro determination of xenobiotic intrinsic clearance (CLint) in trout hepatocytes and subsequent extrapolation to in vivo hepatic clearance (CLH) using the "well-stirred" liver model greatly improved our current practice of bioaccumulation assessment [Han, X., N …

In vitro determination of xenobiotic intrinsic clearance (CLint) in trout hepatocytes and subsequent extrapolation to in vivo hepatic cleara …

10

Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways.

Han X, Szostek B, Yang CH, Cheatham SF, Mingoia RT, Nabb DL, Gannon SA, Himmelstein MW, Jepson GW. Han X, et al. Drug Metab Dispos. 2011 Jul;39(7):1288-93. doi: 10.1124/dmd.111.038299. Epub 2011 Apr 14. Drug Metab Dispos. 2011. PMID: 21493824

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