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Suplatast tosilate inhibits histamine signaling by direct and indirect down-regulation of histamine H1 receptor gene expression through suppression of histidine decarboxylase and IL-4 gene transcriptions.
Shahriar M, Mizuguchi H, Maeyama K, Kitamura Y, Orimoto N, Horio S, Umehara H, Hattori M, Takeda N, Fukui H. Shahriar M, et al. Among authors: fukui h. J Immunol. 2009 Aug 1;183(3):2133-41. doi: 10.4049/jimmunol.0901058. Epub 2009 Jul 13. J Immunol. 2009. PMID: 19596986
Repeated pre-treatment with antihistamines suppresses [corrected] transcriptional up-regulations of histamine H(1) receptor and interleukin-4 genes in toluene-2,4-diisocyanate-sensitized rats.
Mizuguchi H, Hatano M, Matsushita C, Umehara H, Kuroda W, Kitamura Y, Takeda N, Fukui H. Mizuguchi H, et al. Among authors: fukui h. J Pharmacol Sci. 2008 Dec;108(4):480-6. doi: 10.1254/jphs.08222fp. Epub 2008 Dec 10. J Pharmacol Sci. 2008. PMID: 19075512 Free article.
1,477 results