Yang PY - Search Results

1

High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.

Srinivasan R, Tan LP, Wu H, Yang PY, Kalesh KA, Yao SQ. Srinivasan R, et al. Among authors: yang py. Org Biomol Chem. 2009 May 7;7(9):1821-8. doi: 10.1039/b902338k. Epub 2009 Mar 11. Org Biomol Chem. 2009. PMID: 19590777

2

"Click" synthesis of small-molecule inhibitors targeting caspases.

Ng SL, Yang PY, Chen KY, Srinivasan R, Yao SQ. Ng SL, et al. Among authors: yang py. Org Biomol Chem. 2008 Mar 7;6(5):844-7. doi: 10.1039/b718304f. Epub 2008 Feb 4. Org Biomol Chem. 2008. PMID: 18292873

3

Solid-phase synthesis of azidomethylene inhibitors targeting cysteine proteases.

Yang PY, Wu H, Lee MY, Xu A, Srinivasan R, Yao SQ. Yang PY, et al. Org Lett. 2008 May 15;10(10):1881-4. doi: 10.1021/ol800575z. Epub 2008 Apr 12. Org Lett. 2008. PMID: 18407644

4

High-throughput discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry.

Tan LP, Wu H, Yang PY, Kalesh KA, Zhang X, Hu M, Srinivasan R, Yao SQ. Tan LP, et al. Among authors: yang py. Org Lett. 2009 Nov 19;11(22):5102-5. doi: 10.1021/ol9023419. Org Lett. 2009. PMID: 19852491

5

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities.

Yang PY, Liu K, Ngai MH, Lear MJ, Wenk MR, Yao SQ. Yang PY, et al. J Am Chem Soc. 2010 Jan 20;132(2):656-66. doi: 10.1021/ja907716f. J Am Chem Soc. 2010. PMID: 20028024

6

Click-based synthesis and proteomic profiling of lipstatin analogues.

Ngai MH, Yang PY, Liu K, Shen Y, Wenk MR, Yao SQ, Lear MJ. Ngai MH, et al. Among authors: yang py. Chem Commun (Camb). 2010 Nov 28;46(44):8335-7. doi: 10.1039/c0cc01276a. Epub 2010 Jun 24. Chem Commun (Camb). 2010. PMID: 20577697

7

A peptide aldehyde microarray for high-throughput profiling of cellular events.

Wu H, Ge J, Yang PY, Wang J, Uttamchandani M, Yao SQ. Wu H, et al. Among authors: yang py. J Am Chem Soc. 2011 Feb 16;133(6):1946-54. doi: 10.1021/ja109597v. Epub 2011 Jan 19. J Am Chem Soc. 2011. PMID: 21247160

8

Multicolor, one- and two-photon imaging of enzymatic activities in live cells with fluorescently Quenched Activity-Based Probes (qABPs).

Hu M, Li L, Wu H, Su Y, Yang PY, Uttamchandani M, Xu QH, Yao SQ. Hu M, et al. Among authors: yang py. J Am Chem Soc. 2011 Aug 10;133(31):12009-20. doi: 10.1021/ja200808y. Epub 2011 Jul 15. J Am Chem Soc. 2011. PMID: 21732629

9

Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes.

Yang PY, Liu K, Zhang C, Chen GY, Shen Y, Ngai MH, Lear MJ, Yao SQ. Yang PY, et al. Chem Asian J. 2011 Oct 4;6(10):2762-75. doi: 10.1002/asia.201100306. Epub 2011 Jul 8. Chem Asian J. 2011. PMID: 21744505

10

Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.

Yang PY, Wang M, Li L, Wu H, He CY, Yao SQ. Yang PY, et al. Chemistry. 2012 May 21;18(21):6528-41. doi: 10.1002/chem.201103322. Epub 2012 Apr 4. Chemistry. 2012. PMID: 22488888

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