Srinivasan R - Search Results

1

High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.

Srinivasan R, Tan LP, Wu H, Yang PY, Kalesh KA, Yao SQ. Srinivasan R, et al. Org Biomol Chem. 2009 May 7;7(9):1821-8. doi: 10.1039/b902338k. Epub 2009 Mar 11. Org Biomol Chem. 2009. PMID: 19590777

2

Cell-permeable small molecule probes for site-specific labeling of proteins.

Yeo DS, Srinivasan R, Uttamchandani M, Chen GY, Zhu Q, Yao SQ. Yeo DS, et al. Among authors: srinivasan r. Chem Commun (Camb). 2003 Dec 7;(23):2870-1. doi: 10.1039/b309196a. Chem Commun (Camb). 2003. PMID: 14680216

3

Expanded utility of the native chemical ligation reaction.

Yeo DS, Srinivasan R, Chen GY, Yao SQ. Yeo DS, et al. Among authors: srinivasan r. Chemistry. 2004 Oct 4;10(19):4664-72. doi: 10.1002/chem.200400414. Chemistry. 2004. PMID: 15372685 Review.

4

Chemical approaches for live cell bioimaging.

Srinivasan R, Yao SQ, Yeo DS. Srinivasan R, et al. Comb Chem High Throughput Screen. 2004 Sep;7(6):597-604. doi: 10.2174/1386207043328463. Comb Chem High Throughput Screen. 2004. PMID: 15379631 Review.

5

Activity-based fingerprinting of proteases.

Srinivasan R, Huang X, Ng SL, Yao SQ. Srinivasan R, et al. Chembiochem. 2006 Jan;7(1):32-6. doi: 10.1002/cbic.200500340. Chembiochem. 2006. PMID: 16317790 No abstract available.

6

Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases.

Srinivasan R, Uttamchandani M, Yao SQ. Srinivasan R, et al. Org Lett. 2006 Feb 16;8(4):713-6. doi: 10.1021/ol052895w. Org Lett. 2006. PMID: 16468749

7

Methods of using click chemistry in the discovery of enzyme inhibitors.

Srinivasan R, Li J, Ng SL, Kalesh KA, Yao SQ. Srinivasan R, et al. Nat Protoc. 2007;2(11):2655-64. doi: 10.1038/nprot.2007.323. Nat Protoc. 2007. PMID: 18007601

8

Site-specific covalent labeling of proteins inside live cells using small molecule probes.

Chattopadhaya S, Srinivasan R, Yeo DS, Chen GY, Yao SQ. Chattopadhaya S, et al. Among authors: srinivasan r. Bioorg Med Chem. 2009 Feb 1;17(3):981-9. doi: 10.1016/j.bmc.2008.01.043. Epub 2008 Jan 30. Bioorg Med Chem. 2009. PMID: 18261914

9

"Click" synthesis of small-molecule inhibitors targeting caspases.

Ng SL, Yang PY, Chen KY, Srinivasan R, Yao SQ. Ng SL, et al. Among authors: srinivasan r. Org Biomol Chem. 2008 Mar 7;6(5):844-7. doi: 10.1039/b718304f. Epub 2008 Feb 4. Org Biomol Chem. 2008. PMID: 18292873

10

In vivo imaging of a bacterial cell division protein using a protease-assisted small-molecule labeling approach.

Chattopadhaya S, Abu Bakar FB, Srinivasan R, Yao SQ. Chattopadhaya S, et al. Among authors: srinivasan r. Chembiochem. 2008 Mar 25;9(5):677-80. doi: 10.1002/cbic.200700647. Chembiochem. 2008. PMID: 18293290 No abstract available.

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