Searcey M - Search Results

1

Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli.

Watanabe K, Hotta K, Praseuth AP, Searcey M, Wang CC, Oguri H, Oikawa H. Watanabe K, et al. Among authors: searcey m. Chembiochem. 2009 Aug 17;10(12):1965-8. doi: 10.1002/cbic.200900260. Chembiochem. 2009. PMID: 19588480 Free PMC article. No abstract available.

2

Targeting higher-order DNA: beyond the G-quadruplex.

Howell LA, Searcey M. Howell LA, et al. Among authors: searcey m. Chembiochem. 2009 Sep 4;10(13):2139-43. doi: 10.1002/cbic.200900243. Chembiochem. 2009. PMID: 19621410 Review. No abstract available.

3

Stereoselectivity, sequence specificity and mechanism of action of the azinomycin epoxide.

David-Cordonnier MH, Casely-Hayford M, Kouach M, Briand G, Patterson LH, Bailly C, Searcey M. David-Cordonnier MH, et al. Among authors: searcey m. Chembiochem. 2006 Nov;7(11):1658-61. doi: 10.1002/cbic.200600244. Chembiochem. 2006. PMID: 16991169 No abstract available.

4

A small molecule that induces assembly of a four way DNA junction at low temperature.

Howell LA, Waller ZA, Bowater R, O'Connell M, Searcey M. Howell LA, et al. Among authors: searcey m. Chem Commun (Camb). 2011 Aug 7;47(29):8262-4. doi: 10.1039/c1cc12922h. Epub 2011 Jun 24. Chem Commun (Camb). 2011. PMID: 21706079 Free article.

5

Design and synthesis of threading intercalators to target DNA.

Howell LA, Gulam R, Mueller A, O'Connell MA, Searcey M. Howell LA, et al. Among authors: searcey m. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6956-9. doi: 10.1016/j.bmcl.2010.09.128. Epub 2010 Oct 7. Bioorg Med Chem Lett. 2010. PMID: 20980148

6

Synthesis of small molecules targeting multiple DNA structures using click chemistry.

Howell LA, Bowater RA, O'Connell MA, Reszka AP, Neidle S, Searcey M. Howell LA, et al. Among authors: searcey m. ChemMedChem. 2012 May;7(5):792-804. doi: 10.1002/cmdc.201200060. Epub 2012 Feb 29. ChemMedChem. 2012. PMID: 22378532

7

A rapid screen for molecules that form duplex to duplex crosslinks in DNA.

Marín MJ, Rackham BD, Round AN, Howell LA, Russell DA, Searcey M. Marín MJ, et al. Among authors: searcey m. Chem Commun (Camb). 2013 Oct 14;49(80):9113-5. doi: 10.1039/c3cc45600e. Epub 2013 Aug 30. Chem Commun (Camb). 2013. PMID: 23995794

8

Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy.

Rackham BD, Howell LA, Round AN, Searcey M. Rackham BD, et al. Among authors: searcey m. Org Biomol Chem. 2013 Dec 28;11(48):8340-7. doi: 10.1039/c3ob42009d. Epub 2013 Oct 25. Org Biomol Chem. 2013. PMID: 24158749

9

Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2).

Waller ZA, Howell LA, Macdonald CJ, O'Connell MA, Searcey M. Waller ZA, et al. Among authors: searcey m. Biochem Biophys Res Commun. 2014 Apr 25;447(1):128-32. doi: 10.1016/j.bbrc.2014.03.117. Epub 2014 Apr 1. Biochem Biophys Res Commun. 2014. PMID: 24699415

10

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin.

Cominetti MMD, Goffin SA, Raffel E, Turner KD, Ramoutar JC, O'Connell MA, Howell LA, Searcey M. Cominetti MMD, et al. Among authors: searcey m. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4878-4880. doi: 10.1016/j.bmcl.2015.06.014. Epub 2015 Jun 14. Bioorg Med Chem Lett. 2015. PMID: 26115576

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