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Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, Ropero S, Kalluri R, Croce CM, Calin GA, Esteller M. Melo S, et al. Among authors: davalos v. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4394-9. doi: 10.1073/pnas.1014720108. Epub 2011 Feb 28. Proc Natl Acad Sci U S A. 2011. PMID: 21368194 Free PMC article.
Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity.
Léveillé N, Elkon R, Davalos V, Manoharan V, Hollingworth D, Oude Vrielink J, le Sage C, Melo CA, Horlings HM, Wesseling J, Ule J, Esteller M, Ramos A, Agami R. Léveillé N, et al. Among authors: davalos v. Nat Commun. 2011 Oct 25;2:513. doi: 10.1038/ncomms1519. Nat Commun. 2011. PMID: 22027593 Free PMC article.
62 results