Holloway HW - Search Results

1

A cellular model of inflammation for identifying TNF-alpha synthesis inhibitors.

Tweedie D, Luo W, Short RG, Brossi A, Holloway HW, Li Y, Yu QS, Greig NH. Tweedie D, et al. Among authors: holloway hw. J Neurosci Methods. 2009 Oct 15;183(2):182-7. doi: 10.1016/j.jneumeth.2009.06.034. Epub 2009 Jul 5. J Neurosci Methods. 2009. PMID: 19583982 Free PMC article.

2

Thiothalidomides: novel isosteric analogues of thalidomide with enhanced TNF-alpha inhibitory activity.

Zhu X, Giordano T, Yu QS, Holloway HW, Perry TA, Lahiri DK, Brossi A, Greig NH. Zhu X, et al. Among authors: holloway hw. J Med Chem. 2003 Nov 20;46(24):5222-9. doi: 10.1021/jm030152f. J Med Chem. 2003. PMID: 14613324

3

Thalidomide-based TNF-alpha inhibitors for neurodegenerative diseases.

Greig NH, Giordano T, Zhu X, Yu QS, Perry TA, Holloway HW, Brossi A, Rogers JT, Sambamurti K, Lahiri DK. Greig NH, et al. Among authors: holloway hw. Acta Neurobiol Exp (Wars). 2004;64(1):1-9. doi: 10.55782/ane-2004-1486. Acta Neurobiol Exp (Wars). 2004. PMID: 15190675 Free article.

4

Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity.

Luo W, Yu QS, Salcedo I, Holloway HW, Lahiri DK, Brossi A, Tweedie D, Greig NH. Luo W, et al. Among authors: holloway hw. Bioorg Med Chem. 2011 Jul 1;19(13):3965-72. doi: 10.1016/j.bmc.2011.05.029. Epub 2011 May 23. Bioorg Med Chem. 2011. PMID: 21658960 Free PMC article.

5

Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease.

Tweedie D, Ferguson RA, Fishman K, Frankola KA, Van Praag H, Holloway HW, Luo W, Li Y, Caracciolo L, Russo I, Barlati S, Ray B, Lahiri DK, Bosetti F, Greig NH, Rosi S. Tweedie D, et al. Among authors: holloway hw. J Neuroinflammation. 2012 May 29;9:106. doi: 10.1186/1742-2094-9-106. J Neuroinflammation. 2012. PMID: 22642825 Free PMC article.

6

Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.

Zhu X, Yu QS, Cutler RG, Culmsee CW, Holloway HW, Lahiri DK, Mattson MP, Greig NH. Zhu X, et al. Among authors: holloway hw. J Med Chem. 2002 Nov 7;45(23):5090-7. doi: 10.1021/jm020044d. J Med Chem. 2002. PMID: 12408720

7

Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine.

Luo W, Yu QS, Zhan M, Parrish D, Deschamps JR, Kulkarni SS, Holloway HW, Alley GM, Lahiri DK, Brossi A, Greig NH. Luo W, et al. Among authors: holloway hw. J Med Chem. 2005 Feb 24;48(4):986-94. doi: 10.1021/jm049309+. J Med Chem. 2005. PMID: 15715468

8

Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent.

Greig NH, Utsuki T, Ingram DK, Wang Y, Pepeu G, Scali C, Yu QS, Mamczarz J, Holloway HW, Giordano T, Chen D, Furukawa K, Sambamurti K, Brossi A, Lahiri DK. Greig NH, et al. Among authors: holloway hw. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17213-8. doi: 10.1073/pnas.0508575102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275899 Free PMC article.

9

Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine.

Luo W, Yu QS, Kulkarni SS, Parrish DA, Holloway HW, Tweedie D, Shafferman A, Lahiri DK, Brossi A, Greig NH. Luo W, et al. Among authors: holloway hw. J Med Chem. 2006 Apr 6;49(7):2174-85. doi: 10.1021/jm050578p. J Med Chem. 2006. PMID: 16570913 Free PMC article.

10

Apoptotic and behavioral sequelae of mild brain trauma in mice.

Tweedie D, Milman A, Holloway HW, Li Y, Harvey BK, Shen H, Pistell PJ, Lahiri DK, Hoffer BJ, Wang Y, Pick CG, Greig NH. Tweedie D, et al. Among authors: holloway hw. J Neurosci Res. 2007 Mar;85(4):805-15. doi: 10.1002/jnr.21160. J Neurosci Res. 2007. PMID: 17243171

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