Auld DS - Search Results

1

Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening.

Crowe A, Huang W, Ballatore C, Johnson RL, Hogan AM, Huang R, Wichterman J, McCoy J, Huryn D, Auld DS, Smith AB 3rd, Inglese J, Trojanowski JQ, Austin CP, Brunden KR, Lee VM. Crowe A, et al. Among authors: auld ds. Biochemistry. 2009 Aug 18;48(32):7732-45. doi: 10.1021/bi9006435. Biochemistry. 2009. PMID: 19580328 Free PMC article.

2

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. Inglese J, et al. Among authors: auld ds. Nat Chem Biol. 2007 Aug;3(8):466-79. doi: 10.1038/nchembio.2007.17. Nat Chem Biol. 2007. PMID: 17637779 Review.

3

Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease.

Zheng W, Padia J, Urban DJ, Jadhav A, Goker-Alpan O, Simeonov A, Goldin E, Auld D, LaMarca ME, Inglese J, Austin CP, Sidransky E. Zheng W, et al. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13192-7. doi: 10.1073/pnas.0705637104. Epub 2007 Aug 1. Proc Natl Acad Sci U S A. 2007. PMID: 17670938 Free PMC article.

4

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP. Inglese J, et al. Among authors: auld ds. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. doi: 10.1073/pnas.0604348103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864780 Free PMC article.

5

Apparent activity in high-throughput screening: origins of compound-dependent assay interference.

Thorne N, Auld DS, Inglese J. Thorne N, et al. Among authors: auld ds. Curr Opin Chem Biol. 2010 Jun;14(3):315-24. doi: 10.1016/j.cbpa.2010.03.020. Epub 2010 Apr 22. Curr Opin Chem Biol. 2010. PMID: 20417149 Free PMC article. Review.

6

Compound Management for Quantitative High-Throughput Screening.

Yasgar A, Shinn P, Jadhav A, Auld D, Michael S, Zheng W, Austin CP, Inglese J, Simeonov A. Yasgar A, et al. JALA Charlottesv Va. 2008 Apr;13(2):79-89. doi: 10.1016/j.jala.2007.12.004. JALA Charlottesv Va. 2008. PMID: 18496600 Free PMC article.

7

A robotic platform for quantitative high-throughput screening.

Michael S, Auld D, Klumpp C, Jadhav A, Zheng W, Thorne N, Austin CP, Inglese J, Simeonov A. Michael S, et al. Assay Drug Dev Technol. 2008 Oct;6(5):637-57. doi: 10.1089/adt.2008.150. Assay Drug Dev Technol. 2008. PMID: 19035846 Free PMC article. Review.

8

Characterization of chemical libraries for luciferase inhibitory activity.

Auld DS, Southall NT, Jadhav A, Johnson RL, Diller DJ, Simeonov A, Austin CP, Inglese J. Auld DS, et al. J Med Chem. 2008 Apr 24;51(8):2372-86. doi: 10.1021/jm701302v. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363348

9

Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening.

Shukla SJ, Nguyen DT, Macarthur R, Simeonov A, Frazee WJ, Hallis TM, Marks BD, Singh U, Eliason HC, Printen J, Austin CP, Inglese J, Auld DS. Shukla SJ, et al. Among authors: auld ds. Assay Drug Dev Technol. 2009 Apr;7(2):143-69. doi: 10.1089/adt.2009.193. Assay Drug Dev Technol. 2009. PMID: 19505231 Free PMC article.

10

Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase.

Davis MI, Auld DS, Inglese J. Davis MI, et al. Among authors: auld ds. Methods Mol Biol. 2016;1360:47-58. doi: 10.1007/978-1-4939-3073-9_4. Methods Mol Biol. 2016. PMID: 26501901 Free PMC article.

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