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Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo.
Zhou HH, Chin CN, Wu M, Ni W, Quan S, Liu F, Dallas-Yang Q, Ellsworth K, Ho T, Zhang A, Natasha T, Li J, Chapman K, Strohl W, Li C, Wang IM, Berger J, An Z, Zhang BB, Jiang G. Zhou HH, et al. Among authors: li c, li j. Eur J Pharmacol. 2009 Aug 15;616(1-3):346-52. doi: 10.1016/j.ejphar.2009.06.057. Epub 2009 Jul 3. Eur J Pharmacol. 2009. PMID: 19577557
Identification of glucose-dependant insulin secretion targets in pancreatic beta cells by combining defined-mechanism compound library screening and siRNA gene silencing.
Wu W, Shang J, Feng Y, Thompson CM, Horwitz S, Thompson JR, MacIntyre ED, Thornberry NA, Chapman K, Zhou YP, Howard AD, Li J. Wu W, et al. Among authors: li j. J Biomol Screen. 2008 Feb;13(2):128-34. doi: 10.1177/1087057107313763. Epub 2008 Jan 23. J Biomol Screen. 2008. PMID: 18216393
Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells.
Chen XY, Gu XT, Saiyin H, Wan B, Zhang YJ, Li J, Wang YL, Gao R, Wang YF, Dong WP, Najjar SM, Zhang CY, Ding HF, Liu JO, Yu L. Chen XY, et al. Among authors: li j. J Biol Chem. 2012 Aug 31;287(36):30368-75. doi: 10.1074/jbc.M112.375618. Epub 2012 Jul 13. J Biol Chem. 2012. PMID: 22798068 Free PMC article. Clinical Trial.
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