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Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT).
Woods CP, Corrigan M, Gathercole L, Taylor A, Hughes B, Gaoatswe G, Manolopoulos K, Hogan AE, O'Connell J, Stewart PM, Tomlinson JW, O'Shea D, Sherlock M. Woods CP, et al. J Clin Endocrinol Metab. 2015 Apr;100(4):1434-44. doi: 10.1210/jc.2014-4120. Epub 2015 Jan 20. J Clin Endocrinol Metab. 2015. PMID: 25603461 Clinical Trial.
Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?
Sinclair AJ, Walker EA, Burdon MA, van Beek AP, Kema IP, Hughes BA, Murray PI, Nightingale PG, Stewart PM, Rauz S, Tomlinson JW. Sinclair AJ, et al. Among authors: hughes ba. J Clin Endocrinol Metab. 2010 Dec;95(12):5348-56. doi: 10.1210/jc.2010-0729. Epub 2010 Sep 8. J Clin Endocrinol Metab. 2010. PMID: 20826586
Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors.
Arlt W, Biehl M, Taylor AE, Hahner S, Libé R, Hughes BA, Schneider P, Smith DJ, Stiekema H, Krone N, Porfiri E, Opocher G, Bertherat J, Mantero F, Allolio B, Terzolo M, Nightingale P, Shackleton CH, Bertagna X, Fassnacht M, Stewart PM. Arlt W, et al. Among authors: hughes ba. J Clin Endocrinol Metab. 2011 Dec;96(12):3775-84. doi: 10.1210/jc.2011-1565. Epub 2011 Sep 14. J Clin Endocrinol Metab. 2011. PMID: 21917861 Free PMC article.
Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement.
Chortis V, Taylor AE, Schneider P, Tomlinson JW, Hughes BA, O'Neil DM, Libé R, Allolio B, Bertagna X, Bertherat J, Beuschlein F, Fassnacht M, Karavitaki N, Mannelli M, Mantero F, Opocher G, Porfiri E, Quinkler M, Sherlock M, Terzolo M, Nightingale P, Shackleton CH, Stewart PM, Hahner S, Arlt W. Chortis V, et al. Among authors: hughes ba. J Clin Endocrinol Metab. 2013 Jan;98(1):161-71. doi: 10.1210/jc.2012-2851. Epub 2012 Nov 16. J Clin Endocrinol Metab. 2013. PMID: 23162091 Free article. Clinical Trial.
156 results