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Page 1
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.
Yamashita M, Nonaka T, Arai T, Kametani F, Buchman VL, Ninkina N, Bachurin SO, Akiyama H, Goedert M, Hasegawa M. Yamashita M, et al. Among authors: bachurin so. FEBS Lett. 2009 Jul 21;583(14):2419-24. doi: 10.1016/j.febslet.2009.06.042. Epub 2009 Jun 26. FEBS Lett. 2009. PMID: 19560462 Free article.
[New aspects of the pathogenesis of lateral amyotrophic sclerosis].
Skvortsova VI, Bachurin SO, Razinskaia OD, Smirnov AP, Kovrazhkina EA, Pochigaeva KI, Ninkina NN, Shelkovnikova TA, Ustiugov AA. Skvortsova VI, et al. Among authors: bachurin so. Zh Nevrol Psikhiatr Im S S Korsakova. 2011;111(2):4-9. Zh Nevrol Psikhiatr Im S S Korsakova. 2011. PMID: 21510103 Russian. No abstract available.
Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice.
Shelkovnikova TA, Ustyugov AA, Millership S, Peters O, Anichtchik O, Spillantini MG, Buchman VL, Bachurin SO, Ninkina NN. Shelkovnikova TA, et al. Among authors: bachurin so. Neurodegener Dis. 2011;8(6):430-7. doi: 10.1159/000324989. Epub 2011 May 12. Neurodegener Dis. 2011. PMID: 21576917 Free PMC article.
FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein.
Shelkovnikova TA, Ustyugov AA, Smirnov AP, Skvortsova VI, Buchman VL, Bachurin SO, Ninkina NN. Shelkovnikova TA, et al. Among authors: bachurin so. Dokl Biochem Biophys. 2011 May-Jun;438:123-6. doi: 10.1134/S1607672911030045. Epub 2011 Jul 3. Dokl Biochem Biophys. 2011. PMID: 21725888 No abstract available.
Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice.
Bachurin SO, Shelkovnikova TA, Ustyugov AA, Peters O, Khritankova I, Afanasieva MA, Tarasova TV, Alentov II, Buchman VL, Ninkina NN. Bachurin SO, et al. Neurotox Res. 2012 Jul;22(1):33-42. doi: 10.1007/s12640-011-9299-y. Epub 2011 Dec 17. Neurotox Res. 2012. PMID: 22179976 Free PMC article.
Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.
Shelkovnikova TA, Peters OM, Deykin AV, Connor-Robson N, Robinson H, Ustyugov AA, Bachurin SO, Ermolkevich TG, Goldman IL, Sadchikova ER, Kovrazhkina EA, Skvortsova VI, Ling SC, Da Cruz S, Parone PA, Buchman VL, Ninkina NN. Shelkovnikova TA, et al. Among authors: bachurin so. J Biol Chem. 2013 Aug 30;288(35):25266-25274. doi: 10.1074/jbc.M113.492017. Epub 2013 Jul 18. J Biol Chem. 2013. PMID: 23867462 Free PMC article.
195 results