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Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.
Stankovic T, Hubank M, Cronin D, Stewart GS, Fletcher D, Bignell CR, Alvi AJ, Austen B, Weston VJ, Fegan C, Byrd PJ, Moss PA, Taylor AM. Stankovic T, et al. Blood. 2004 Jan 1;103(1):291-300. doi: 10.1182/blood-2003-04-1161. Epub 2003 Sep 4. Blood. 2004. PMID: 12958068 Free article.
Rac1 and Rac2 GTPases in haematopoiesis.
Weston VJ, Stankovic T. Weston VJ, et al. Among authors: stankovic t. Bioessays. 2004 Mar;26(3):221-4. doi: 10.1002/bies.20017. Bioessays. 2004. PMID: 14988923
Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-kappaB survival pathway signaling.
Weston VJ, Austen B, Wei W, Marston E, Alvi A, Lawson S, Darbyshire PJ, Griffiths M, Hill F, Mann JR, Moss PA, Taylor AM, Stankovic T. Weston VJ, et al. Among authors: stankovic t. Blood. 2004 Sep 1;104(5):1465-73. doi: 10.1182/blood-2003-11-4039. Epub 2004 May 13. Blood. 2004. PMID: 15142883 Free article.
A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival.
Alvi AJ, Austen B, Weston VJ, Fegan C, MacCallum D, Gianella-Borradori A, Lane DP, Hubank M, Powell JE, Wei W, Taylor AM, Moss PA, Stankovic T. Alvi AJ, et al. Among authors: stankovic t. Blood. 2005 Jun 1;105(11):4484-91. doi: 10.1182/blood-2004-07-2713. Epub 2005 Feb 3. Blood. 2005. PMID: 15692065 Free article.
Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.
Austen B, Skowronska A, Baker C, Powell JE, Gardiner A, Oscier D, Majid A, Dyer M, Siebert R, Taylor AM, Moss PA, Stankovic T. Austen B, et al. Among authors: stankovic t. J Clin Oncol. 2007 Dec 1;25(34):5448-57. doi: 10.1200/JCO.2007.11.2649. Epub 2007 Oct 29. J Clin Oncol. 2007. PMID: 17968022
177 results