Rothbart SB - Search Results

1

Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition.

Racanelli AC, Rothbart SB, Heyer CL, Moran RG. Racanelli AC, et al. Among authors: rothbart sb. Cancer Res. 2009 Jul 1;69(13):5467-74. doi: 10.1158/0008-5472.CAN-08-4979. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549896 Free PMC article.

2

Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas.

Rothbart SB, Racanelli AC, Moran RG. Rothbart SB, et al. Cancer Res. 2010 Dec 15;70(24):10299-309. doi: 10.1158/0008-5472.CAN-10-1873. Cancer Res. 2010. PMID: 21159649 Free PMC article.

3

AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells.

Agarwal S, Bell CM, Rothbart SB, Moran RG. Agarwal S, et al. Among authors: rothbart sb. J Biol Chem. 2015 Nov 13;290(46):27473-86. doi: 10.1074/jbc.M115.665133. Epub 2015 Sep 21. J Biol Chem. 2015. PMID: 26391395 Free PMC article.

4

Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner.

Harlow ML, Chasse MH, Boguslawski EA, Sorensen KM, Gedminas JM, Kitchen-Goosen SM, Rothbart SB, Taslim C, Lessnick SL, Peck AS, Madaj ZB, Bowman MJ, Grohar PJ. Harlow ML, et al. Among authors: rothbart sb. Clin Cancer Res. 2019 Jun 1;25(11):3417-3429. doi: 10.1158/1078-0432.CCR-18-3511. Epub 2019 Feb 5. Clin Cancer Res. 2019. PMID: 30723142 Free PMC article.

5

From histones to ribosomes: a chromatin regulator tangoes with translation.

Rothbart SB, Dickson BM, Strahl BD. Rothbart SB, et al. Cancer Discov. 2015 Mar;5(3):228-30. doi: 10.1158/2159-8290.CD-15-0073. Cancer Discov. 2015. PMID: 25749972 Free PMC article.

6

The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation.

Vaughan RM, Rothbart SB, Dickson BM. Vaughan RM, et al. Among authors: rothbart sb. J Biol Chem. 2019 Oct 25;294(43):15724-15732. doi: 10.1074/jbc.RA119.010160. Epub 2019 Sep 3. J Biol Chem. 2019. PMID: 31481468 Free PMC article.

7

Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes.

Ali M, Daze KD, Strongin DE, Rothbart SB, Rincon-Arano H, Allen HF, Li J, Strahl BD, Hof F, Kutateladze TG. Ali M, et al. Among authors: rothbart sb. J Biol Chem. 2015 Sep 18;290(38):22919-30. doi: 10.1074/jbc.M115.669333. Epub 2015 Jul 30. J Biol Chem. 2015. PMID: 26229108 Free PMC article.

8

Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14.

Enríquez P, Krajewski K, Strahl BD, Rothbart SB, Dowen RH, Rose RB. Enríquez P, et al. Among authors: rothbart sb. J Biol Chem. 2021 Oct;297(4):101145. doi: 10.1016/j.jbc.2021.101145. Epub 2021 Aug 30. J Biol Chem. 2021. PMID: 34473995 Free PMC article.

9

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin.

Simon JM, Parker JS, Liu F, Rothbart SB, Ait-Si-Ali S, Strahl BD, Jin J, Davis IJ, Mosley AL, Pattenden SG. Simon JM, et al. Among authors: rothbart sb. J Biol Chem. 2015 Oct 23;290(43):26088-102. doi: 10.1074/jbc.M115.654459. Epub 2015 Sep 3. J Biol Chem. 2015. PMID: 26338712 Free PMC article.

10

A physical basis for quantitative ChIP-sequencing.

Dickson BM, Tiedemann RL, Chomiak AA, Cornett EM, Vaughan RM, Rothbart SB. Dickson BM, et al. Among authors: rothbart sb. J Biol Chem. 2020 Nov 20;295(47):15826-15837. doi: 10.1074/jbc.RA120.015353. Epub 2020 Sep 29. J Biol Chem. 2020. PMID: 32994221 Free PMC article.

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