Shinde SN - Search Results

1

Cdc25B dual-specificity phosphatase inhibitors identified in a high-throughput screen of the NIH compound library.

Johnston PA, Foster CA, Tierno MB, Shun TY, Shinde SN, Paquette WD, Brummond KM, Wipf P, Lazo JS. Johnston PA, et al. Among authors: shinde sn. Assay Drug Dev Technol. 2009 Jun;7(3):250-65. doi: 10.1089/adt.2008.186. Assay Drug Dev Technol. 2009. PMID: 19530895 Free PMC article.

2

Development and optimization of high-throughput in vitro protein phosphatase screening assays.

Tierno MB, Johnston PA, Foster C, Skoko JJ, Shinde SN, Shun TY, Lazo JS. Tierno MB, et al. Among authors: shinde sn. Nat Protoc. 2007;2(5):1134-44. doi: 10.1038/nprot.2007.155. Nat Protoc. 2007. PMID: 17546004

3

Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual-specificity protein phosphatase inhibitors.

Johnston PA, Foster CA, Shun TY, Skoko JJ, Shinde S, Wipf P, Lazo JS. Johnston PA, et al. Assay Drug Dev Technol. 2007 Jun;5(3):319-32. doi: 10.1089/adt.2007.066. Assay Drug Dev Technol. 2007. PMID: 17638532

4

HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus.

Johnston PA, Phillips J, Shun TY, Shinde S, Lazo JS, Huryn DM, Myers MC, Ratnikov BI, Smith JW, Su Y, Dahl R, Cosford ND, Shiryaev SA, Strongin AY. Johnston PA, et al. Assay Drug Dev Technol. 2007 Dec;5(6):737-50. doi: 10.1089/adt.2007.101. Assay Drug Dev Technol. 2007. PMID: 18181690

5

Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents.

Johnston PA, Soares KM, Shinde SN, Foster CA, Shun TY, Takyi HK, Wipf P, Lazo JS. Johnston PA, et al. Among authors: shinde sn. Assay Drug Dev Technol. 2008 Aug;6(4):505-18. doi: 10.1089/adt.2008.151. Assay Drug Dev Technol. 2008. PMID: 18699726 Free PMC article.

6

Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B.

Keinan S, Paquette WD, Skoko JJ, Beratan DN, Yang W, Shinde S, Johnston PA, Lazo JS, Wipf P. Keinan S, et al. Org Biomol Chem. 2008 Sep 21;6(18):3256-63. doi: 10.1039/b806712k. Epub 2008 Jul 15. Org Biomol Chem. 2008. PMID: 18802630 Free PMC article.

7

Design and synthesis of a library of tetracyclic hydroazulenoisoindoles.

Brummond KM, Mao S, Shinde SN, Johnston PJ, Day BW. Brummond KM, et al. Among authors: shinde sn. J Comb Chem. 2009 May-Jun;11(3):486-94. doi: 10.1021/cc900024p. J Comb Chem. 2009. PMID: 19366169 Free PMC article.

8

Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments.

Soares KM, Blackmon N, Shun TY, Shinde SN, Takyi HK, Wipf P, Lazo JS, Johnston PA. Soares KM, et al. Among authors: shinde sn. Assay Drug Dev Technol. 2010 Apr;8(2):152-74. doi: 10.1089/adt.2009.0247. Assay Drug Dev Technol. 2010. PMID: 20070233 Free PMC article.

9

Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits.

Dudgeon DD, Shinde S, Hua Y, Shun TY, Lazo JS, Strock CJ, Giuliano KA, Taylor DL, Johnston PA, Johnston PA. Dudgeon DD, et al. J Biomol Screen. 2010 Aug;15(7):766-82. doi: 10.1177/1087057110375304. Epub 2010 Jul 16. J Biomol Screen. 2010. PMID: 20639499

10

Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.

Dudgeon DD, Shinde SN, Shun TY, Lazo JS, Strock CJ, Giuliano KA, Taylor DL, Johnston PA, Johnston PA. Dudgeon DD, et al. Among authors: shinde sn. Assay Drug Dev Technol. 2010 Aug;8(4):437-58. doi: 10.1089/adt.2010.0281. Assay Drug Dev Technol. 2010. PMID: 20662736 Free PMC article.

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