Lebrec HN - Search Results

1

Summary of a workshop on nonclinical and clinical immunotoxicity assessment of immunomodulatory drugs.

Piccotti JR, Lebrec HN, Evans E, Herzyk DJ, Hastings KL, Burns-Naas LA, Gourley IS, Wierda D, Kawabata TT. Piccotti JR, et al. Among authors: lebrec hn. J Immunotoxicol. 2009 Mar;6(1):1-10. doi: 10.1080/15476910802656440. J Immunotoxicol. 2009. PMID: 19519157 Free article.

2

Apoptotic responses in squamous carcinoma and epithelial cells to small-molecule toll-like receptor agonists evaluated with automated cytometry.

Inglefield JR, Larson CJ, Gibson SJ, Lebrec H, Miller RL. Inglefield JR, et al. J Biomol Screen. 2006 Sep;11(6):575-85. doi: 10.1177/1087057106288051. Epub 2006 Jun 7. J Biomol Screen. 2006. PMID: 16760371

3

Evaluation of a lymph node proliferation assay for its ability to detect pharmaceuticals with potential to cause immune-mediated drug reactions.

Weaver JL, Chapdelaine JM, Descotes J, Germolec D, Holsapple M, House R, Lebrec H, Meade J, Pieters R, Hastings KL, Dean JH. Weaver JL, et al. J Immunotoxicol. 2005 Jan 1;2(1):11-20. doi: 10.1080/15476910590930100. J Immunotoxicol. 2005. PMID: 18958655 Free article.

4

Survey: immune function and immunotoxicity assessment in dogs.

Lebrec H, O'Lone R, Freebern W, Komocsar W, Moore P. Lebrec H, et al. J Immunotoxicol. 2012 Jan-Mar;9(1):1-14. doi: 10.3109/1547691X.2011.592163. Epub 2011 Nov 7. J Immunotoxicol. 2012. PMID: 22059464 Free article.

5

A summary of meeting proceedings for 'Measuring immune responses in non-human primates for drug development-opportunities and challenges for predicting human efficacy and immunotoxicity'.

Kamperschroer C, Kaur A, Lebrec H. Kamperschroer C, et al. J Immunotoxicol. 2012 Jan-Mar;9(1):108-20. doi: 10.3109/1547691X.2011.631610. J Immunotoxicol. 2012. PMID: 22299718 Free article. No abstract available.

6

HESI/FDA workshop on immunomodulators and cancer risk assessment: Building blocks for a weight-of-evidence approach.

Lebrec H, Brennan FR, Haggerty H, Herzyk D, Kamperschroer C, Maier CC, Ponce R, Preston BD, Weinstock D, Mellon RD. Lebrec H, et al. Regul Toxicol Pharmacol. 2016 Mar;75:72-80. doi: 10.1016/j.yrtph.2015.12.018. Epub 2015 Dec 29. Regul Toxicol Pharmacol. 2016. PMID: 26743742 Free article.

7

Summary of a workshop on preclinical and translational safety assessment of CD3 bispecifics.

Kamperschroer C, Shenton J, Lebrec H, Leighton JK, Moore PA, Thomas O. Kamperschroer C, et al. J Immunotoxicol. 2020 Dec;17(1):67-85. doi: 10.1080/1547691X.2020.1729902. J Immunotoxicol. 2020. PMID: 32100588 Free article.

8

Drug hypersensitivity reactions: review of the state of the science for prediction and diagnosis.

Pallardy M, Bechara R, Whritenour J, Mitchell-Ryan S, Herzyk D, Lebrec H, Merk H, Gourley I, Komocsar WJ, Piccotti JR, Balazs M, Sharma A, Walker DB, Weinstock D. Pallardy M, et al. Toxicol Sci. 2024 Jun 26;200(1):11-30. doi: 10.1093/toxsci/kfae046. Toxicol Sci. 2024. PMID: 38588579 Free PMC article. Review.

9

Overview of the nonclinical quality and toxicology testing for recombinant biopharmaceuticals produced in mammalian cells.

Lebrec H, Narayanan P, Nims R. Lebrec H, et al. J Appl Toxicol. 2010 Jul;30(5):387-96. doi: 10.1002/jat.1551. J Appl Toxicol. 2010. PMID: 20589744 Review.

10

An inter-laboratory retrospective analysis of immunotoxicological endpoints in non-human primates: T-cell-dependent antibody responses.

Lebrec H, Cowan L, Lagrou M, Krejsa C, Neradilek MB, Polissar NL, Black L, Bussiere J. Lebrec H, et al. J Immunotoxicol. 2011 Jul-Sep;8(3):238-50. doi: 10.3109/1547691X.2011.587473. Epub 2011 Jun 21. J Immunotoxicol. 2011. PMID: 21692639 Free article.

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