Kraytsberg Y - Search Results

1

Quantitative analysis of somatic mitochondrial DNA mutations by single-cell single-molecule PCR.

Kraytsberg Y, Bodyak N, Myerow S, Nicholas A, Ebralidze K, Khrapko K. Kraytsberg Y, et al. Methods Mol Biol. 2009;554:329-69. doi: 10.1007/978-1-59745-521-3_21. Methods Mol Biol. 2009. PMID: 19513684

2

Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues.

Nekhaeva E, Bodyak ND, Kraytsberg Y, McGrath SB, Van Orsouw NJ, Pluzhnikov A, Wei JY, Vijg J, Khrapko K. Nekhaeva E, et al. Among authors: kraytsberg y. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5521-6. doi: 10.1073/pnas.072670199. Epub 2002 Apr 9. Proc Natl Acad Sci U S A. 2002. PMID: 11943860 Free PMC article.

3

mtLOH (mitochondrial loss of heteroplasmy), aging, and 'surrogate self'.

Nekhaeva E, Kraytsberg Y, Khrapko K. Nekhaeva E, et al. Among authors: kraytsberg y. Mech Ageing Dev. 2002 Apr 30;123(8):891-8. doi: 10.1016/s0047-6374(02)00026-x. Mech Ageing Dev. 2002. PMID: 12044937 Review.

4

Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process?

Kraytsberg Y, Nekhaeva E, Bodyak NB, Khrapko K. Kraytsberg Y, et al. Mech Ageing Dev. 2003 Jan;124(1):49-53. doi: 10.1016/s0047-6374(02)00169-0. Mech Ageing Dev. 2003. PMID: 12618006 Review.

5

Where and when do somatic mtDNA mutations occur?

Khrapko K, Ebralidse K, Kraytsberg Y. Khrapko K, et al. Among authors: kraytsberg y. Ann N Y Acad Sci. 2004 Jun;1019:240-4. doi: 10.1196/annals.1297.040. Ann N Y Acad Sci. 2004. PMID: 15247022 Review.

6

Single-molecule PCR: an artifact-free PCR approach for the analysis of somatic mutations.

Kraytsberg Y, Khrapko K. Kraytsberg Y, et al. Expert Rev Mol Diagn. 2005 Sep;5(5):809-15. doi: 10.1586/14737159.5.5.809. Expert Rev Mol Diagn. 2005. PMID: 16149882 Review.

7

On the timing and the extent of clonal expansion of mtDNA deletions: evidence from single-molecule PCR.

Nicholas A, Kraytsberg Y, Guo X, Khrapko K. Nicholas A, et al. Among authors: kraytsberg y. Exp Neurol. 2009 Aug;218(2):316-9. doi: 10.1016/j.expneurol.2009.04.029. Epub 2009 May 6. Exp Neurol. 2009. PMID: 19426731 Free PMC article.

8

Collection of isolated cells for studying mitochondrial DNA mutations within individual cells.

Kraytsberg Y, Bodyak N, Myerow S, Nicholas A, Ebralidze K, Khrapko K. Kraytsberg Y, et al. Methods Mol Biol. 2009;554:315-27. doi: 10.1007/978-1-59745-521-3_20. Methods Mol Biol. 2009. PMID: 19513683

9

Mitochondrial DNA deletions in mice in men: substantia nigra is much less affected in the mouse.

Guo X, Kudryavtseva E, Bodyak N, Nicholas A, Dombrovsky I, Yang D, Kraytsberg Y, Simon DK, Khrapko K. Guo X, et al. Among authors: kraytsberg y. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1159-62. doi: 10.1016/j.bbabio.2010.04.005. Epub 2010 Apr 11. Biochim Biophys Acta. 2010. PMID: 20388490 Free PMC article.

10

Are somatic mitochondrial DNA mutations relevant to our health? A challenge for mutation analysis techniques.

Kraytsberg Y, Nicholas A, Khrapko K. Kraytsberg Y, et al. Expert Opin Med Diagn. 2007 Sep;1(1):109-16. doi: 10.1517/17530059.1.1.109. Expert Opin Med Diagn. 2007. PMID: 23489273

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